AIM This study was conducted to examine the potential of mycotoxin binder in ceasing zearalenone (ZEN) effect on mice reproduction. ZEN mycotoxin can induce reactive oxygen species that may cause damage and cell death. ZEN is estrogenic so that it may affect the reproductive organs failure. MATERIALS AND METHODS Mycotoxin binder administration to female mice exposed to ZEN was aimed to count ...

Recently, the use of substances that can suppress or reduce absorption, promote the excretion of mycotoxins or modify their mode of action in feed, so-called mycotoxin binders, has been officially allowed in the European Union as technological feed additives. The influence of the addition of mycotoxin binders to animal feed on the analytical performance of the official methods for the determina...

The aim of this study was to characterize 27 feed additives marketed as mycotoxin binders and to screen them for their in vitro zearalenone (ZEN) adsorption. Firstly, 27 mycotoxin binders, commercially available in Belgium and The Netherlands, were selected and characterized. Characterization was comprised of X-ray diffraction (XRD) profiling of the mineral content and d-spacing, determination ...

Lon W. Whitlow Department of Animal Science North Carolina State University Raleigh, NC 27695 Phone: 919-515-7602 Fax: 919-515-2152 Email: [email protected] Summary Considerable research has been directed at finding methods to prevent toxicity of mycotoxins. Some of the approaches have included mycotoxin separation from contaminated feeds, detoxification and inactivation. Detoxification and ...

It is recognized that mycotoxins can cause a variety of adverse health effects in animals, including altered gastrointestinal barrier function. It is the aim of the present study to determine whether mycotoxin-contaminated diets can alter the oral bioavailability of the antibiotics doxycycline and paromomycin in pigs, and whether a mycotoxin adsorbing agent included into diets interacts with th...

In order to assess the in vivo efficacy of mycotoxin binders, specific toxicokinetic parameters should be measured according to European guidelines. For this purpose, an absorption model in pigs is described with emphasis on absorption kinetics. Pigs received a single oral bolus of the mycotoxin deoxynivalenol alone or in combination with active carbon (applied as mycotoxin binder). After admin...

A study was conducted with an objective to compare the efficacy of bentonite (BT), Spirulina platensis (SP) and glucomannan mycotoxin binders (GMA) on aflatoxicosis in broiler breeders. Three levels of AF, three binders and combination of different levels of AF with binders were evaluated. The Aflatoxin B1 (AF) fed at the levels of 300, 400 and 500ppb for three periods, each with duration of th...

A study was conducted with an objective to compare the efficacy of bentonite (BT), Spirulina platensis (SP) and glucomannan mycotoxin binders (GMA) on aflatoxicosis in broiler breeders. Three levels of AF, three binders and combination of different levels of AF with binders were evaluated. The AF fed at the levels of 300, 400 and 500ppb for three periods, each with duration of three weeks in br...