TO TH E ED ITO R: The prevalence of noncardiac chest pain (NCCP) differs by the type of study performed: hospital-based studies, community-based studies or general practice studies. In the previous two studies, we reported that 38%-41% of NCCP in average aged subjects had gastroesophageal reflux disease (GERD) diagnosed by endoscopy and 24-hour esophageal pH monitoring, with similar protocol to...

TO TH E ED ITO R: Noncardiac chest pain (NCCP) is not only a difficult disorder to define but also a heterogenous disorder with many potential causes. Gastroesophageal reflux disease (GERD) represents as one of the most common gastroenterologic causes of NCCP. Seo et al suggested that the prevalence of GERD was 30 percent in young patients with NCCP. In addition, the proton pump inhibitor (PPI)...

Background/Aims Gastroesophageal reflux disease (GERD) is the most common cause of non-cardiac chest pain (NCCP). Currently available data reveal a weak relationship between NCCP and dysmotility. Moreover, it is unclear why some refluxes are perceived as heartburn and others as NCCP. We aimed to evaluate the role of the reflux pattern and the esophageal motility in patients with NCCP. Methods...

Pediatric NCCP may be characterized by recurrent pain accompanied by emotional distress and functional impairment. This paper reviews and critiques literature on pediatric noncardiac chest pain (NCCP) and introduces a theoretical conceptualization to guide future study of NCCP in children and adolescents. A developmentally informed biopsychosocial conceptualization of NCCP etiology is proposed ...

Noncardiac chest pain (NCCP) is one of the most common esophageal symptoms and lacks a clearly defined mechanism. The most common cause of NCCP is gastroesophageal reflux disease (GERD). One of the accepted mechanisms of NCCP in a patient without GERD has been altered visceral sensitivity. Mast cells may play a role in visceral hypersensitivity in irritable bowel syndrome. In this case, a patie...

BACKGROUND Non-cardiac chest pain (NCCP) is a common complaint. Our aim was to present a detailed description of the costs of patients with NCCP compared to patients with acute myocardial infarction (AMI) and Angina Pectoris (AP) from a societal perspective. METHODS Data on healthcare utilization and annual societal costs, including direct healthcare costs and indirect costs due to productivi...

BACKGROUND/AIMS Noncardiac chest pain (NCCP) is a very common disorder world-wide and gastroesophageal reflux disease (GERD) is known to be the most common cause. The prevalence of NCCP may tend to decrease with increasing age. However, there is little report about young aged NCCP. The aim of this study was to examine the prevalence of GERD and to evaluate the efficacy of proton pump inhibitor ...

AIM Population-based assessment of noncardiac chest pain (NCCP) is lacking. The aim of this study was to evaluate the prevalence, psychosocial factors and health seeking behaviour of NCCP in southern Chinese. METHODS A total of 2 209 ethnic Hong Kong Chinese households were recruited to participate in a telephone survey to study the epidemiology of NCCP using the Rose angina questionnaire, a ...

Noncardiac chest pain (NCCP) is not only a difficult disorder to define but is also complex in characterization and treatment. Patients with NCCP are a challenge to primary care and subspecialty services such as cardiology and gastroenterology. NCCP is often a heterogeneous disorder with many potential causes including gastroenterologic diagnoses. This article presents the current evidence for ...

Continuing the theme of number game from the previous editorial, it is time to initiate a wider discussion on the complex number game embedded the Indian National Cancer Control Programme (NCCP). NCCP is replete with numbers: number of cancer cases, number of cancer centres, number of registries, number of machines, number of tobacco users, leading numbers, receding numbers, missing numbers, du...