نتایج جستجو برای: neun

تعداد نتایج: 870  

Journal: :Württembergisch Franken 2023

2017
Ahmed Yousef John L. Robinson David J. Irwin Matthew D. Byrne Linda K. Kwong Edward B. Lee Yan Xu Sharon X. Xie Lior Rennert EunRan Suh Vivianna M. Van Deerlin Murray Grossman Virginia M.-Y. Lee John Q. Trojanowski

Frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) is associated with the accumulation of pathological neuronal and glial intracytoplasmic inclusions as well as accompanying neuron loss. We explored if cortical neurons detected by NeuN decreased with increasing TDP-43 inclusion pathology in the postmortem brains of 63 patients with sporadic and familial FTLD-TDP. Semi-automated...

Journal: :avicenna journal of neuro psycho physiology 0
fahimeh ghasemi moravej cell therapy division of endometrium and endometriosis research center, hamadan university of medical sciences, hamadan, ir iran; anatomy department, school of medicine, hamadan university of medical sciences, hamadan, ir iran iraj amiri cell therapy division of endometrium and endometriosis research center, hamadan university of medical sciences, hamadan, ir iran; anatomy department, school of medicine, hamadan university of medical sciences, hamadan, ir iran siamak shahidi neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran mehdi mehdizadeh faculty of advanced technologies in medicine, cellular and molecular research center, iran university of medical sciences, tehran, ir iran asrin rahimi anatomy department, school of medicine, hamadan university of medical sciences, hamadan, ir iran banafsheh esmaeilzadeh faculty of medicine, anatomy department, bushehr university of medical sciences, bushehr, ir iran

conclusions these results suggest a negative correlation between mdma administration and adult hippocampal neurogenesis. results our results showed that mdma administration caused a decrease in neun expression in the experimental group compared with the control group. objectives due to the effect of neurogenesis on memory and learning, in this study, we investigated the effects of mdma on neun ...

Journal: :Proceedings of the Imperial Academy 1933

Journal: :DMW - Deutsche Medizinische Wochenschrift 1898

Journal: :The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1996
H K Wolf R Buslei R Schmidt-Kastner P K Schmidt-Kastner T Pietsch O D Wiestler I Blümcke

The monoclonal antibody A60 specifically recognizes the DNA-binding, neuron-specific protein NeuN, which is present in most neuronal cell types of vertebrates. In this study we demonstrate the potential use of NeuN as a diagnostic neuronal marker using a wide range of formalin-fixed, paraffin-embedded human surgical and autopsy specimens from the central and peripheral nervous system. After mic...

2011
B. Kate Dredge Kirk B. Jensen

Anti-NeuN (Neuronal Nuclei) is a monoclonal antibody used extensively to specifically detect post-mitotic neurons. Anti-NeuN reactivity is predominantly nuclear; by western it detects multiple bands ranging in molecular weight from 45 kDa to >75 kDa. Expression screening putatively identified R3hdm2 as NeuN; however immunoprecipitation and mass spectrometry of the two major NeuN species at 45-5...

2015
V. V. Gusel’nikova D. E. Korzhevskiy

The NeuN protein is localized in nuclei and perinuclear cytoplasm of most of the neurons in the central nervous system of mammals. Monoclonal antibodies to the NeuN protein have been actively used in the immunohistochemical research of neuronal differentiation to assess the functional state of neurons in norm and pathology for more than 20 years. Recently, NeuN antibodies have begun to be appli...

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