UNLABELLED INTRODUCTION Plexiform neurofibroma of the larynx is a rare disease. In this report, we present a plexiform neurofibroma in the arytenoids and neurofibroma in the parapharynx detected coincidently. CASE PRESENTATION A 56-year-old Asian woman presented with respiratory distress and episodes of apnea at night. A solitary mass from the left arytenoids was found to be nearly obstruc...

Neurofibroma is a benign neoplasm of the peripheral nerve, which occurs as multiple tumours in neurofibromatosis type 1 (NF1) or as a solitary tumour with no association with NF1. Malignant change is sometimes reported in neurofibroma in NF1, but there are few reports of malignant transformation of solitary neurofibroma. We report here a case of malignant change in a solitary sclerotic neurofib...

Pigmented neurofibroma is a rare variant of neurofibroma showing melanin production. The clinical diagnosis is difficult to establish requiring the histopathological examination to differentiate between the melanotic neurofibroma and other pigmented tumours. We report an unusual case of a huge, recurrent, pigmented neurofibroma with extended, macroscopically striking pigmentation in a 45 year o...

Neurofibroma is a localized discrete mass of benign nerve sheath tumour in the peripheral nervous system. Mostly present as skin lesions. Solitary neurofibroma may occur in deep soft tissue or subcutaneous plane in rare cases associated with syndromes like NF1. The neurofibroma most commonly present as skin lesions as isolated soft papules or nodules arising in any cutaneous site. Present case ...

Article history: Received: 3 Oct 2013 Accepted: 20 Nov 2013 Available online: 28 Apr 2014 ZJRMS 2014 July; 16(7): 42-44 Neurofibroma is a benign neoplasm derived from peripheral nerve cells. Neurofibroma can occur as a solitary tumor also it may associate with neurofibromatosis. Intraosseous neurofibroma is a rare tumor particularly in the oral cavity. So far, few cases of solitary intraosseous...

Plexiform neurofibroma is more commonly seen in the orbit, neck, back, and inguinal region. It is extremely rare in the submandibular gland. These lesions rarely transform into malignancy but are locally infiltrative and can lead to haemorrhage. Therefore, plexiform neurofibroma should always be considered during differential diagnosis while excising a submandibular gland mass. We present here ...

Segmental neurofibromatosis type 5 (NF5) is a rare form of NF, in which the cutaneous and/or neural changes are confined to one region of the body. It is often underdiagnosed or undetected due to the absence of symptoms. Inheritance of NF is different from other types of NF. Intraosseous neurofibromas are rare tumors which develop from nerves supplying the periosteum or nerves following the int...

Plexiform neurofibroma of the submandibular gland is an extremely rare tumor. Herein, we report a case of plexiform neurofibroma in a patient with a von Recklinghausen's disease (NF-1) who presented with a submandibular mass mimicking a submandibular gland tumor. Complete surgical excision provides the best treatment and final diagnosis. A neurofibroma should be considered in the differential d...

The cell surface antigen distribution on traumatic neuroma Schwann cells and neurofibroma Schwann-like cells was characterized using mono clonal antibodies that define melanoma-associated antigens. Immunofluorescence staining of cultured cells, immunoprecipitation of radioiodinated antigens from cells placed in short-term cultures, and immunoperoxidase staining of frozen tissue sections reveale...