a 28-year-old man with neurofibromatosis type 1(nf1) presented with a tumor in the sciatic nerve and femoral nerve. the differential diagnosis of malignant peripheral nerve sheath tumor was based on clinical, radiological, and histological evidence. the tumor apparently originated in sciatic nerve at the posterior aspect of the left thigh. the lesion was resected totally without neural damage t...

The authors report a case of simultaneously occurring neurofibroma and schwannoma of the sciatic nerve and discuss the complementary aspects of MR and US. The schwannoma was well-defined and showed distal enhancement on sonographic evaluation, whereas the neurofibroma was ill-defined; both tumors were hypoechoic. T1- and T2-weighted MR images revealed similar signal characteristics of the two t...

BACKGROUND Paralysis of the external popliteal sciatic nerve is a frequent pathological condition that occurs after trauma. However, etiologies other than trauma, such as tumors, are also possible. The sensory collaterals of the external popliteal sciatic nerve have a small territory of innervation at the knee, and tumors involving these nerves become symptomatic after compression of the motor ...

A 26-year-old man with neurofibromatosis type 1 (NF1) presented with a giant malignant schwannoma of the sciatic nerve. The differential diagnosis of malignant peripheral nerve sheath tumor (MPNST) was based on clinical, radiological, and histological evidence. The tumor apparently originated in a spinal plexiform neurofibroma. The lesion was resected totally without neural damage to the sciati...

Objective(s): To investigate the systemic and local immune status of two surgical rat models of sciatic nerve injury, a crushed sciatic nerve, and a sciatic nerve transection Materials and Methods:Twenty-four adult male Sprague-Dawley rats were randomly divided into three groups: sham-operation (control group), sciatic nerve crush, and sciatic nerve transaction. Sciatic nerve surgery was perfor...

objective(s): we investigated the histopathological effects of metamizole sodium (ms) on the sciatic nerve.  materials and methods: this study was performed using 48 adult male wistar albino rats. ten groups were constituted with 6 rats in each group. ms injection into the sciatic nerve (group 1), ms injection into the muscle [group 3 (50 mg/kg, 0.4 ml) and group 5 (50 mg/kg, 0.8 ml)], ms injec...

objective: as effectiveness of the autologous graft in the repair of long nerve defects is very limited an effective substitute is needed. this study was conducted to determine the poled polyvinylidene fluoride (pvdf) tube as an alternative to nerve autograft. materials and methods: the left sciatic nerve was transected in 45 male wistar rats. the animals were then divided randomly into three g...