background: we aimed to compare clinical effects of sugammadex versus combination of anticholinergic-anticholinesterase agents for reversing of nondepolarizing neuromuscular block in pediatric patients.materials and methods: a total of 60 pediatric patients  whom should be performed general anesthesia in the supine position were enrolled to this randomized double-blinded clinical trial.fentanyl...

botulinum toxin a (bta) inhibits presynaptic release of acetylcholine at the neuromuscular junction and has reportedly been successful in the treatment of spastic disorders.to evaluate the effect of botulinum toxin on cerebral palsied children with spastic or mixed type of the disease, especially those patiens having spasticity as a cardinal symptom without joint contracture, we designed the fo...

to compare intubating conditions and hemodynamic changes between bonfils intubation fiberscope and macintosh laryngoscopy without administering neuromuscular blocking drugs (nmbds). methods: in this randomized controlled trial,80 male and female patients, scheduled for elective surgery, aged 15 to 60 years, asa class ii or i, non-obese, non smokers, without anticipated difficult intubation; wer...

Neuromuscular blockade, induced by neuromuscular blocking agents, has allowed prescribed immobility, improved surgical exposure, optimal airway management conditions, and facilitated mechanical ventilation. However, termination of the effects of neuromuscular blocking agents has, until now, remained limited. A novel cyclodextrin encapsulation process offers improved termination of the paralytic...