نتایج جستجو برای: neuropathic pain

تعداد نتایج: 246876  

Journal: :Archives of neurology 2003
Robert H Dworkin Miroslav Backonja Michael C Rowbotham Robert R Allen Charles R Argoff Gary J Bennett M Catherine Bushnell John T Farrar Bradley S Galer Jennifer A Haythornthwaite David J Hewitt John D Loeser Mitchell B Max Mario Saltarelli Kenneth E Schmader Christoph Stein David Thompson Dennis C Turk Mark S Wallace Linda R Watkins Sharon M Weinstein

Chronic neuropathic pain, caused by lesions in the peripheral or central nervous system, comes in many forms. We describe current approaches to the diagnosis and assessment of neuropathic pain and discuss the results of recent research on its pathophysiologic mechanisms. Randomized controlled clinical trials of gabapentin, the 5% lidocaine patch, opioid analgesics, tramadol hydrochloride, and t...

2014
Valéria Martinez Nadine Attal Bertrand Vanzo Eric Vicaut Jean Michel Gautier Didier Bouhassira Michel Lantéri-Minet

BACKGROUND AND AIMS The French Pain Society published guidelines for neuropathic pain management in 2010. Our aim was to evaluate the compliance of GPs with these guidelines three years later. METHODS We used "e" case vignette methodology for this non interventional study. A national panel of randomly selected GPs was included. We used eight "e" case-vignettes relating to chronic pain, differ...

Journal: :Pain 2008
Didier Bouhassira Michel Lantéri-Minet Nadine Attal Bernard Laurent Chantal Touboul

We conducted a large nationwide postal survey to estimate the prevalence of chronic pain with or without neuropathic characteristics in the French general population. A questionnaire aimed at identifying chronic pain (defined as daily pain for at least 3 months), evaluating its intensity, duration and body locations, was sent to a representative sample of 30,155 subjects. The DN4 questionnaire ...

Journal: :Molecular Pain 2006
Mohammed A Nassar Mark D Baker Alessandra Levato Rachel Ingram Giovanna Mallucci Stephen B McMahon John N Wood

Changes in sodium channel activity and neuronal hyperexcitability contribute to neuropathic pain, a major clinical problem. There is strong evidence that the re-expression of the embryonic voltage-gated sodium channel subunit Nav1.3 underlies neuronal hyperexcitability and neuropathic pain. Here we show that acute and inflammatory pain behaviour is unchanged in global Nav1.3 mutant mice. Surpri...

2016
R. Baron A. Binder N. Attal R. Casale A.H. Dickenson R‐D. Treede

BACKGROUND AND OBJECTIVE Low back pain (LBP) is one of the most common chronic pain conditions. This paper reviews the available literature on the role of neuropathic mechanisms in chronic LBP and discusses implications for its clinical management, with a particular focus on pharmacological treatments. DATABASES AND DATA TREATMENT Literature searches were performed in PubMed, key pain congres...

Journal: :Current treatment options in neurology 2002
Gil I. Wolfe Richard J. Barohn

Treatment of neuropathic pain is the primary focus of management for many patients with painful peripheral neuropathies. Neuropathic pain is a common feature of many peripheral neuropathies including those associated with diabetes, uremia, HIV infection, and alcohol abuse. Pain is also present in the majority of patients with idiopathic sensory and sensorimotor polyneuropathies. A growing numbe...

Journal: :Science-Business eXchange 2013

Journal: :Archives of Neurology 2001

Journal: :Medical Council 2017

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