نتایج جستجو برای: neuroprotective effect

تعداد نتایج: 1652601  

Journal: :basic and clinical neuroscience 0
mohammad zamani majid katebi mehdi mehdizadeh farzaneh mohamadzadeh mansooreh soleimani

introduction: preliminary studies have con.rmed reduction in cell death following treatment with antioxidants. according to this .nding we study the relationship between consumption of coq10 and expression of bax and bcl2 in hippocampus following ischemia/reperfusion as proteins involved in cell programmed death or apoptosis. methods: we studied the protective role of coq10 against ischemia-rep...

Journal: :bulletin of emergency and trauma 0
ehsanali alibai fahim baghban department of neurosurgery shiraz neurosciences research center shiraz university of medical sciences majid reza farrokhi navideh mohebali mohammad hossein ashraf

objective: to determine the effects of recombinant human erythropoietin (rhepo) on functional outcome and disability of patients with traumatic cervical spinal cord injury (sci).  methods: this was a randomized, double blind, placebo controlled clinical trial being performed in nemazee and shahid rajaei hospitals of shiraz during a 3-year period from 2011 to 2014. a total number of 20 patients ...

Journal: :iranian journal of basic medical sciences 0
reza kowsari department of biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran rezvan yazdian-robati department of biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran bibi marjan razavi targeted drug delivery research center, department of pharmacodinamy and toxicology, mashhad university of medical sciences, mashhad, iran atena pourtaji pharmaceutical research center, department of pharmacodynamy and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran maryam ghorbani department of pharmacology and toxicology, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran hediye moghadam-omranipour department of biotechnology, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s): erythropoietin (epo), is a 34kda glycoprotein hormone, which belongs to type 1 cytokine superfamily. epo involves in erythrocyte maturation through inhibition of apoptosis in erythroid cells. besides its main function, protective effects of epo in heart and brain tissues have been reported. epo has a critical role in development, growth, and homeostasis of brain. furthermore epo h...

Journal: :Ibnosina Journal of Medicine and Biomedical Sciences 2023

We read the article “Predictors of Metformin Side Effects in Patients with Newly Diagnosed Type 2 Diabetes Mellitus” esteemed “Ibnosina Journal Medicine and Biomedical Sciences” great interest. Alibrahim et al assessed possible variables that may influence development metformin side effects. The most common effect was diarrhea. authors found female sex, high fasting blood glucose, increased bod...

2013
Seok Hwan Kim Joo Hyun Park Yu Jeong Kim Ki Ho Park

PURPOSE This study aimed to investigate the neuroprotective effect of resveratrol in an optic nerve transection (ONT) model and to identify the neuroprotective mechanism of resveratrol in retinal ganglion cells (RGCs). METHODS ONT and retrograde labeling were performed in Sprague-Dawley rats. Various concentrations of resveratrol were injected intravitreally immediately after ONT. The number ...

Journal: :iranian biomedical journal 0
fatemeh dehghan mohammad khaksari elham abbasloo nader shahrokhi

background: in previous studies, the neuroprotective effect of 17&beta-estradiol; in diffuse traumatic brain injury has been shown. this study used ici 182,780, a non-selective estrogen receptor antagonist, to test the hypothesis that the neuroprotective effect of 17&beta-estradiol; in traumatic brain injury is mediated by the estrogen receptors. methods: the ovariectomized rats were divided in...

2013
Amarjot Kaur Grewal Amteshwar Singh Jaggi Avtar Chand Rana Nirmal Singh

The present study was designed to investigate the putative effect of neurosteroid modulation on global ischaemia-reperfusion-induced cerebral injury in mice. Bilateral carotid artery occlusion followed by reperfusion, produced a significant rise in cerebral infarct size along with impairment of grip strength and motor coordination in Swiss albino mice. Administration of carbamazepine (16 mg/kg,...

Journal: :avicenna journal of phytomedicine 0
ahmad ghorbani neyshabur faculty of medical sciences, neyshabur, i. r. iran hassan rakhshandeh pharmacological research center of medicinal plants, faculty of medicine, mashhad university of medical sciences, mashhad, i. r. iran elham asadpour department of pharmacology, department of new sciences and technologies, faculty of medicine, mashhad university of medical sciences, mashhad, i. r. iran

objective: this study was planned to investigate whethercoriandrum sativum (c. sativum) is capable of protecting neurons against glucose/serum deprivation (gsd)-induced cytotoxicity. material and methods: the pc12 cells were cultivated for 24 h in standard media (high-glucose dmem containing fetal bovine serum) or for 6 h in gsd condition (glucose-free dmem, without serum) in the absence or pre...

Journal: :Neural Regeneration Research 2016

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