background: control of the phosphorus in hemodialysis patients is very important and can be done in many ways. the purpose of the study was to compare the effects of nicotinic acid and lanthanum carbonate on hyperphosphatemia in the hemodialysis patients. materials and methods: this double-blind randomized clinical trial was done in imam hossein hospital (shahroud, iran) in 2014. the participan...

The hydroxycarboxylic acid family of receptors (ENSFM00500000271913, nomenclature as agreed by the NC-IUPHAR Subcommittee on Hydroxycarboxylic [36, 12]) respond to organic acids, including endogenous hydroxy carboxylic acids 3-hydroxy butyric and L-lactic acid, well lipid lowering agents nicotinic (niacin), acipimox acifran [53, 60, 65]. These were provisionally described receptors, although sh...

An α7 nicotinic acetylcholine receptor sequence was cloned from Rhesus monkey (Macaca mulatta). This clone differs from the mature human α7 nicotinic acetylcholine receptor in only four amino acids, two of which are in the extracellular domain. The monkey α7 nicotinic receptor was characterized in regard to its functional responses to acetylcholine, choline, cytisine, and the experimental α7-se...

This article presents the results of quantitative determination fatty acids and vitamins, contained in Acanthophyllum pungens plants, belonging to Caryophyllaceae family growing Khantagi, located near city Kentau, Turkestan region. As a result gas chromatography acids, obtained as studies plant materials, it has been found that contains 87% unsaturated 13% saturated acids. Saturated acids: myri...

Krehl et al. (1, 2) have observed that the inclusion of large amounts of corn grits in a low protein diet produced a growth retardation in rats, which was corrected by the addition of either nicot,inic acid or L-tryptophan. The beneficial action of the amino acid is now attributed to its role as a biological precursor of nicotinic acid (3-5). It is not necessary to postulate the existence of a ...

This study found that in Tris-HCl buffer, the resonance light scattering (RLS) intensity of the Eu(3+)-nicotinic acid system can be greatly enhanced by nucleic acids and the enhanced intensity is proportional to the concentration of nucleic acid in the range of 7 x 10(-8)-1 x 10(-5 ) g x mL(-1) for fsDNA, and its detection limit is 2 x 10(-8 ) g x mL(-1). Based on this, a new method for the det...

Nicotinic acid is widely used in the food, pharmaceutical and biochemical industries. Fermentation technology for the production of nicotinic acid in particular has been known for more than a century and acid have been produced in aqueous solutions. Reactive liquid-liquid extraction for the recovery of the organic acids by a suitable extractant has been found to be a promising alternative to th...

Nicotinic acid and niacinamide are used in a variety of therapeutic application as important components of the co-factors, nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate. Decreasing the adverse effects will improve the stability and absorption of nicotinic acid. Nicotinic acid aspartic acid dipeptide and tetrapeptide were synthesized via Fmoc solid-phase synth...

Proadrenomedullin N-terminal 20 peptide (PAMP-[1-20]; ARLDVASEFRKKWNKWALSR-amide) is a potent hypotensive and catecholamine release-inhibitory peptide released from chromaffin cells. We studied the mechanism of PAMP action and how its function is linked to structure. We tested human PAMP-[1-20] on catecholamine secretion in PC12 pheochromocytoma cells and found it to be a potent, dose-dependent...