When group-housed female mice are exposed to male mice, male pheromones induce female ovarian cyclicity resulting in a majority of the females entering estrus and spontaneous ovulation on the third night following introduction of the male--the so-called Whitten effect. We previously demonstrated that females mating on the third night after being housed with a male mouse ovulated significantly m...

Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics (SORA), Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, United Kingdom, Department of Public Health and Epidemiology, Swiss Tropical Institute, P.O. Box, CH-4002 Basel, Switzerland, Institute of Pathology, University Hospital B...

INTRODUCTION The brain glutamate neurotransmitter system and its NMDA (N-methyl-D-aspartate) receptors in the nucleus accumbens play an important role in the incidence of sensitivity and addiction. The present study examined the inhibitory effect of glutamate NMDA receptors in the nucleus accumbens in response to chronic stress. METHODS After the unilateral and bilateral placement of cannula(...

abstract since gasoil due to the aromatics of the most important environmental pollutants and is one of the oil with many applications. according to its damaging effects on living organisms and human beings, the purpose of this study was to investigate the effects of gasoil on the parameters of liver, white rat race was albino nmri. the 40 mice in 4 groups, adult male mice were divided into con...

introduction: in the present study, the effects of light cure on wound healing of mice’s skin with complete thickness were studied. materials and methods: forty male mice of nmri race were placed randomly into two groups of examination and control. under aseptic and unconscious conditions, a circular wound of 6 mm width with complete thickness of skin was made on the back of each mice. the surg...

By applying a newly developed ELISA technique for determining biologically active intact glucagon-like peptide [GLP-1, GLP-1-(7-36)amide] in mouse, plasma baseline GLP-1 in normal NMRI mice was found to be normally distributed (4.5 +/- 0.3 pmol/l; n = 72). In anesthetized mice, gastric glucose (50 or 150 mg) increased plasma GLP-1 levels two- to threefold (P < 0.01). The simultaneous increase i...

Disruption of peripheral circadian rhyme pathways dominantly leads to metabolic disorders. Studies on circadian rhythm proteins in the heart indicated a role for Clock or Per2 in cardiac metabolism. In contrast to Clock(-/-), Per2(-/-) mice have larger infarct sizes with deficient lactate production during myocardial ischemia. To test the hypothesis that cardiac Per2 represents an important reg...

One challenge of squamous cell carcinoma of the head and neck (SCCHN) chemotherapy is a small percentage of tumor cells that arrest in the G0 phase of the cell cycle and are thus not affected by chemotherapy. This could be one reason for tumor recurrence at a later date. The recruitment of these G0-arresting cells into the active cell cycle and th...

conclusions it can be concluded that the nettle extract can reduce blood glucose levels in diabetic mice, at least partly, by influencing the glut2 gene expression in mice liver. results the results showed that the nettle extract significantly decreased high levels of blood glucose (p < 0.001). the nettle extract also had a preventive effect on decrease in body weight. in addition, the results ...