Paul Ehrlich, in 1909, initiated the development for targeted delivery when he envisaged a drug delivery mechanism that would target directly to diseased cell. Drug targeting can be defined as the ability to direct a therapeutic agent specifically to desired site of action with little or no interaction with non target tissue 1 . In noisome, the vesicles forming amphiphile is a non-ionic surfact...

Inflammation is a pathologic condition that includes a wide range of diseases namely neurodegenerative diseases. Several natural anti-inflammatory components have been identified in plant extracts used in traditional medicine for the relief of inflammation. Herbal medicine is showing difficulty in crossing the blood-brain barrier (BBB). So that the ability to pass the BBB is the main concern fo...

niosomes are non-ionic surfactant vesicles that have potential applications in the delivery of hydrophilic and hydrophobic drugs. the topical form of n-acetyl glucosamine (nag) recently has been considered in the treatment of hyperpigmentation disorders due to its inhibitory effect on thyrosinase enzymes in melanocytes. to improve nag penetration into the skin we formulated the drug in niosomes...

I analyze Shakespeare’s racialization of noise in The Tempest as an acousmatic phenomenon and suggest how the — sound whose source remains hidden is imagined a weapon resistance that racialized noisome Other could use to resist aristocratic colonial power. play echoes Algonquian-speaking Powhatan singing Tsenacommacah mode warfare against English Virginia 1611 with Caliban his companions’ (Step...

Drug delivery systems using colloidal particulate carriers such as liposomes and niosomes have distinct advantages over conventional dosage forms. However, there remain significant problems like instability in the general application of liposomes and niosomes for drug delivery. Proniosome have the potential to become a promising drug carrier in order to give stability to niosomal drug delivery ...

Delivery of drug through topical route represents a most convenient and novel approach. The major difficulty arises while delivering a drug through skin is its action as a natural barrier nature which makes it difficult for most drugs to penetrate into and permeate through it. Conventional topical formulations have not proved to be effective in dermal delivery of drug. Novel drug delivery syste...

meenakshikanwar(at)yahoo.com Abstract Over the past several years, treatment of infectious diseases and immunization has undergone a paradigm shift. Stemming from the nanobiotechnology research, not only a large number of disease-specific biologicals have been developed, but also enormous efforts have been made to effectively deliver these biologicals. Niosomes are vesicular systems prepared fr...

To prepare niosomes containing rifampicin were prepared using various nonionic surfactants of sorbitan ester class and cholesterol in 50:60 (1:1.2) percent mol fraction ratios for sustain release. To improve the dissolution rate of noisome are prepare handshaking method using Surfactants and cholesterol (150 μmol) in 50:60 (1:1.2) percent mol fraction ratio. The percent of drug estimated to be ...

in this study canthaxanthin was produced by dietzia natronolimnaea hs1 and used for incorporation in niosomes after extraction. effect of rotational speed of rotary vacuum evaporator flask (100 and 150 rpm), canthaxanthin concentration (0, 1 and 2 microgram/ milliliter), concentration of poly ethylene glycol 400 (0, 0.1 and 0.2 %), surfactant type (tween 60 and 80, span 60 and 80) and surfactan...