Recent experimental evidence suggests that octacalcium phosphate (OCP) is a necessary precursor to hydroxyapaptite in the amorphous-crystalline transformation that occurs after the spon..: taneous precipitation of calcium phosphate in the pH range 7.00-9.25. The transformation appears to occur by heterogeneous nucleation of OCP by the initially formed amorphous calcium phosphate (ACP) phase. AC...

In vitro studies on interactions between amelogenins and calcium phosphate crystals are critical for elucidating biomineralization mechanisms of tooth enamel. This work was aimed at investigating the effects of native porcine amelogenins on octacalcium phosphate (OCP) crystal growth in a gelatin gel. We prepared OCP mineral discs by circulating calcium and phosphate solutions on the opposite en...

objective: furcal perforation is an undesirable complication that may occur during root canal therapy and seriously compromises the prognosis of endodontic treatment. the prognosis of furcal perforation repair depends on the prevention of bacterial infection of the perforation site. thus, use of a biocompatible material for complete sealing of the perforation site is critically important. this ...

Calcium phosphate (Ca-P) coatings on zirconia bone implants have a great potential to improve the osseointegration of already existing ceramic implants, owing to their bone-bonding ability and high osteoconductive characteristics. In our study, we have prepared three different kinds of Ca-P coatings, namely the octacalcium phosphate (OCP), hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP)...

UNLABELLED To understand early mineralization events, we studied living murine calvarial tissue by Raman spectroscopy using fibroblast growth factor 2 (FGF2)-soaked porous beads. We detected increased levels of a transient phase resembling octacalcium phosphate in sutures undergoing premature suture closure. INTRODUCTION Several calcium phosphates have been postulated as the earliest inorgani...

Dissolution of the (100) face of octacalcium phosphate (OCP) single crystal in weak acidic solutions (pH = 6.5; 25 ̊C) was observed in situ using atomic force microscopy. Monomolecular steps (2.0 nm high) were observed; they originated from etch pits or crystal edges. Advancement of the dissolution process led to precipitation of nanoparticles as small as ~10 nm even though the solution was unde...

Structural features of some calcium phosphates of biological interest are described. Structure of hydroxyapatite (OHAp), considered as the prototype for the inorganic component of bones and teeth is discussed with respect to the kinds and locations of ionic substitutions. Octacalcium phosphate (OCP), is a probable precursor in biological mineralization. OCP has a layer type structure, with one ...

The spherical porous granules of octacalcium phosphate (OCP) and hydroxyapatite (HA) have the potential for applications in scaffolds bone regeneration. alpha-tricalcium were immersed a pH 5.0 buffer solution that contained 0.1 mM ascorbic acid (AscP), an osteogenesis-promoting drug, at 60 °C. This resulted fabrication AscP-loaded HA/OCP granules. OCP HA phases concentrated surface interior gra...