Tuberculosis (TB) diagnostics are centralised, requiring long-distance transportation of specimens in most resource-limited settings. We evaluated the ability of OMNIgene.SPUTUM (OM-S) to obviate cold-chain transport of TB specimens. A two-arm (same-day and after 5 days sample processing) study was conducted to assess contamination rates and Mycobacterium tuberculosis viability in OM-S-treated ...

In the course of screening for antibacterial antibiotics from actinomycetes, a new antibiotic, OM704 A, has been isolated from the culture broth of strain OM-704, a soil isolate identified as Streptomyces sp. This antibiotic was active against Gram-positive bacteria. The present paper deals with the taxonomy of strain OM-704 and the fermentation, isolation and biological and physicochemical pro...

Metal complex of pioglitazone hydrochloride (PLZ) drug with Ni(II) ion is synthesized and characterized using analytical data, molar conductance, IR, UV-Vis, magnetic, mass spectral and XRD studies. From the analytical data, the complex is proposed to have general formula [(C 19 H 19 N 2 O 3 S)+ 2 Ni]2Cl-. The conductometric titration using monovariation method reveals that complex is L 2 M typ...

BACKGROUND The prevalence of repeated otitis media (OM) increased during the 1980s, but it is unknown if the increase has continued. OBJECTIVES To determine trends in the prevalence of OM, early-onset OM, and repeated OM among US children from 1988 to 1994 and to identify factors that may explain any observed changes. METHODS The Third National Health and Nutrition Examination Survey was ad...

Human oncostatin M (OM) is a M(r) 28,000 glycoprotein that has been shown to regulate cell proliferation and differentiation. The biological activities of OM can be mediated by two different heterodimeric receptor complexes, the leukemia inhibitory factor (LIF)/OM shared receptor and the OM-specific receptor. In this study, we have examined the growth-regulatory effect of OM on 10 breast cancer...

BACKGROUND Complementary and alternative medicine (CAM) is popular with patients, yet how patients use CAM in relation to orthodox medicine (OM) is poorly understood. AIM To explore how patients integrate CAM and OM when self-managing chronic illness. DESIGN OF STUDY Qualitative analysis of interviews. METHOD Semi-structured interviews were conducted with individuals attending private CAM...

Staphylococcus aureus is the most common cause of the difficult-to-treat osteomyelitis (OM). To better diagnose and manage S. aureus OM, especially for severe and long duration cases, indicators for risk prediction and severity evaluation are needed. Here, 139 clinical S. aureus isolates from orthopedic infections were divided into OM group (60 isolates from 60 OM patients) and non-OM group (79...

Optic morphology (Om) mutants associated with insertions of the tom transposable element at each of three tested loci are neomorphs as defined by the phenotypic equivalence of +/+/Om with +/Om and of +/Om/Om with Om/Om. Mutants behaving as suppressors of Om mutants and mapping to at least six loci are recovered from the same source and in similar frequency as Om mutants. The semidominant and no...

Oncostatin M (OM) is a 28-kD glycoprotein that exhibits a panoply of biologic effects. Based on histologic observations of increased splenic megakaryocytes in nude mice implanted with an OM-secreting cell line, the thrombocytopoietic properties of OM in mice were investigated in culture and in vivo. Alone, OM did not induce megakaryocytic colony formation, but in combination with murine interle...

Purpose: To evaluate speech recognition in noise on elderly, new users of hearing aids with directional microphones and noise reduction, and check which feature provides better speech intelligibility. Methods: The participants were 36 individuals between 60 and 87 years old with sensorineural hearing loss from mild to moderately severe. The Sentence List test in Brazilian Portuguese was applied...