BACKGROUND Although previous studies have identified high levels of drug-related harm in Thailand, little is known about illicit drug overdose experiences among Thai drug users. We sought to investigate non-fatal overdose experiences and responses to overdose among a community-recruited sample of injection drug users (IDU) in Bangkok, Thailand. METHODS Data for these analyses came from IDU pa...

background: skin lesions and blistering in the overdose patient, most notably associated with barbiturate overdoses, are commonly referred to as coma blisters, 'barb blisters', or 'barb burns'. we present a patient who was noted to have skin lesions including bullae and blistering following a prolonged coma after quetiapine overdose. case report: a 27 year old male presented to our institution ...

tramadol is used in treatment of moderate to severe pain. nowadays tramadol overdose is one of the common emergencies. naloxone is an antagonist which is used as a first step of treatment in these patients. this study was designed to evaluate the seizurogenic effects of naloxone in tramadol overdose. a number of 124 patients with the diagnosis of tramadol overdose were divided to receive low-do...

BACKGROUND Medication overdose accounts for >80% of hospital presentations for self-harm. Previous research has identified typical characteristics of medication overdose cases; however, these cases have not been well differentiated from other similar presentations, namely (1) illicit drug overdose and (2) self-harm by means other than overdose. METHOD A 12-month audit of medication overdose c...

AIMS This study assessed overdose and naloxone administration knowledge among current or former opioid abusers trained and untrained in overdose-response in the United States. DESIGN AND PARTICIPANTS Ten individuals, divided equally between those trained or not trained in overdose recognition and response, were recruited from each of six sites (n = 62). SETTING US-based overdose training an...

AIMS Accidental drug overdose contributes substantially to mortality among drug users. Multi-drug use has been documented as a key risk factor in overdose and overdose mortality in several studies. This study investigated the contribution of multiple drug combinations to overdose mortality trends. DESIGN We collected data on all overdose deaths in New York City between 1990 and 1998 using rec...

AIMS Methadone treatment has been shown to be an effective intervention that can lower the risk of heroin-induced overdose death. Recent reports have suggested increases in methadone-induced overdose deaths in several locations in the USA and in Europe. This study investigated the role of methadone and opiates in accidental overdose deaths in New York City. DESIGN We analysed data from the Of...

benzodiazepine overdose is the most commonly encountered drug overdose in iran. it has been reported by many authors that flumazenil possesses highly specific antagonistic activity on central benzodiazepine receptors. we conducted a prospective study on 150 patients brought to the toxicology emergency ward in loghman-hakim hospital with benzodiazepine overdose to assess the efficacy of flumazen...

AIMS To estimate the extent and nature of overdose and factors associated with overdose among injecting drug users in London. DESIGN Three hundred and twelve current injecting drug users were recruited and interviewed in community settings by a team of "privileged access interviewers". MEASUREMENTS A structured questionnaire was used that covered the following areas: demographic characteris...

INTRODUCTION Emergency departments (EDs) may be high-yield venues to address opioid deaths with education on both overdose prevention and appropriate actions in a witnessed overdose. In addition, the ED has the potential to equip patients with nasal naloxone kits as part of this effort. We evaluated the feasibility of an ED-based overdose prevention program and described the overdose risk knowl...