clavulanic acid is produced industrially by fermentation of streptomyces clavuligerus and researches have increased its production by strain improvement, recombinant dna technology, and media composition and growth condition optimization. the main objective of this study was to increase the level of clavulanic acid production from streptomyces clavuligerus (dsm 738), using uv irradiation. after...

NVA waste is a common activity in practically all construction projects and can affect the performance of those as whole. In Cikarang, West Java, this also occurred PT “XYZ” Warehouse Building Project. The goal study was to ascertain how XYZ's warehouse project affected associated with Overproduction, Inventory, Defect, Motion, Transportation, Processing (Over processing), Waiting. study's find...

The effect of the overproduction of SecF encoded by the tac-secF gene on a plasmid on the synthesis of other Sec proteins was studied in Escherichia coli. SecF overproduction resulted in the simultaneous overproduction of SecD encoded by the tac-secD gene on a plasmid. Deletion of the orf6 gene, located downstream of the secF gene, had no effect on SecD overproduction. A pulse-chase experiment ...

Tn5 transposase (Tnp) overproduction is lethal to Escherichia coli. Tnp overproduction causes cell filamentation, abnormal chromosome segregation, and an increase in anucleated cell formation. There are two simple explanations for the observed phenotype: induction of the SOS response or of the heat shock response. The data presented here show that overproduction of Tnp neither induces an SOS re...

The physiological and regulatory effects of overproduction of five cold shock proteins (CSPs) of Lactococcus lactis were studied. CspB, CspD, and CspE could be overproduced at high levels (up to 19% of the total protein), whereas for CspA and CspC limited overproduction (0.3 to 0.5% of the total protein) was obtained. Northern blot analysis revealed low abundance of the cspC transcript, indicat...

Abstract We use inventory write‐downs to differentiate opportunistic and non‐opportunistic overproduction measures. posit that is positively associated with future because generally leads excess inventory, while (to inflate earnings) negatively decrease earnings. find change‐based proxies (deviations from past behaviour) are the likelihood of write‐downs, whereas residual‐based industry norms) ...

Airway mucus overproduction is one of the most common symptoms of asthma that causes severe clinical outcomes in patients. Despite the effectiveness of general asthma therapies, specific treatments that prevent mucus overproduction in asthma patients remain lacking. Recent studies have found that activation of GABAA receptors (GABAAR) is important for promoting mucus oversecretion in lung airwa...