The oxidation rates for conjugated linoleic acid (CLA), linoleic acid (LA), and their methyl and ethyl esters were measured in aqueous and solvent systems by the induction period method. In an aqueous system, the initiation rate was almost the same for all the samples, except for ethyl conjugated linoleate (ECL). The propagation rate, oxidizability, and kinetic chain length were different for t...

background: hypertensive patients are highly susceptible to oxidizability. although hypertension is common among iranians, few data are available about lipid oxidation status in the involved people. the aim of this study was to evaluate the relationship between serum lipids levels and susceptibility of lipids to oxidation in hypertensive patients. materials and method: fasting serum lipids and ...

Oxidizability of lipids in homogeneous solution varies linearly with the extent of their unsaturation. In vitro cellular, as well as in vivo, studies of oxidizability have generally relied upon chemical indicators of peroxidation such as thiobarbituric acid-reactive substances. To examine the oxidizability of lipids in cells, we have measured oxygen uptake and, using electron paramagnetic reson...

BACKGROUND Present study describe the in vitro model of plasma oxidation of patients with different lipid profile, that can be correlated to their invivo plasma oxidizability in order to find the arterial diseases prone patient groups. METHOD The method applied here to measure the invitro plasma oxidizability, accounts a convenient way that can be well suited in any clinical laboratory settin...

OBJECTIVE To investigate differences in LDL oxidizability by glycemic status within the Insulin Resistance Atherosclerosis Study cohort. RESEARCH DESIGN AND METHODS LDL oxidizability (lag time and oxidation rate) after exposure to copper was compared among 352 subjects with normal glucose tolerance (NGT), impaired glucose tolerance (IGT), newly diagnosed type 2 diabetes, and known type 2 diab...

The effects of six flavonoids viz., apigenin, genistein, morin, naringin, pelargonidin and quercetin on the susceptibility of low-density lipoprotein (LDL) to oxidative modification were investigated. Flavonoids were added to plasma and incubated for 3 hr at 37 degrees C, and the LDL fraction was separated by ultracentrifugation. Oxidizability of LDL was estimated by measuring conjugated diene ...

Caloric restriction (CR), which increases longevity and retards age-associated diseases in laboratory rodents, is being evaluated in nonhuman primate trials. CR reduces oxidative stress in rodents and appears to improve risk factors for cardiovascular disease in nonhuman primates. We tested the hypothesis that low-density lipoprotein (LDL) oxidizability is reduced in two monkey species (rhesus ...

OBJECTIVE To investigate the changes in plasma lipids and lipoproteins, low-density lipoprotein (LDL) oxidizability, and plasma homocysteine during postmenopausal sequential 3-monthly hormone replacement therapy. DESIGN Open longitudinal prospective study. SETTING Gynecological outpatient department of a university hospital. PATIENT(S) Thirty-nine healthy nonhysterectomized postmenopausal...

The decreased oxidizability of plasma lipoproteins is related to the increased vitamin E intake and its association with a relatively lower incidence of coronary heart disease has been proposed. We investigated the effect of the in vivo vitamin E supplementation on the oxidizability of serum lipids in patients with ischemic heart disease and a moderate hypercholesterolemia. Thirty-two patients ...

Objective: Diabetes is the most common metabolic disease. One of the most common problems in diabetic patients is atherosclerotic cardiovascular disease which induced by hyperlipidemia. Also there has been currently great interest in the potential contribution of oxidative stress in development of diabetes complications. The present study was performed to associate between lipid oxidizability a...