The radiolytic decomposition of oxytetracycline and effects of inorganic ions were studied. The removal efficiency of oxytetracycline , 30 mg/L, was 99% at the irradiation dose of 0.7 kGy. Chloride , sulfate , nitrite , nitrate and phosphate had effects on oxytetracycline degradation. Especially , nitrite and nitrate showed the significant inhibition effect on the radiolytic degradation of oxyt...

Oxytetracycline: source and mechanisms of resistance. Oxytetracycline (Terramycin) is a naturally produced tetracycline antibiotic of Streptomyces rimosus, with a spectrum of activity similar to chlortetracycline and tetracycline and remarkable thermostability (16). In plant agriculture, oxytetracycline is used in the USA primarily on pear and apple for fire blight management. Oxytetracycline i...

In a microcosm study, two aquatic macrophytes, Egeria densa and Ceratophyllum demersum were exposed to nominal concentrations of 0, 5, 20, 50, and 250 microg/L oxytetracycline (n=3), plus 20 microg/L oxytetracycline amended with additional nitrogen (N) and phosphorus (P). Responses were monitored bi-weekly over a six-week exposure period. Both plant species exhibited a significant decline in gr...

For animal use only 2 5 6 0 6 4 Liquamycin LA-200 (oxytetracycline injection) is a sterile, preconstituted solution of the broad-spectrum antibiotic oxytetracycline. Each mL contains 200 mg of oxytetracycline base as oxytetracycline dihydrate, and on a w/v basis, 40.0% 2-pyrrolidone, 5.0% povidone, 1.8% magnesium oxide, 0.2% sodium formaldehyde sulfoxylate (as a preservative), monoethanolamine ...

Oxytetracycline ((2Z,4S,4aR,5S,5aR,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino-5,6,10,11,12a-pentahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione) is a member of tetracycline antibiotics family and is widely administered to farm animals for the purpose of therapeutical treatment and health protection. Increasing attention has been paid to the environmental fate of oxytet...

in the egg shells when the eggs were studied in UV-light (Fig. 1). Control eggs did not fluoresce. The concentration of oxytetracycline in the egg shell, albumen, and yolk was measured by UV-absorption spectrofluorometry (Hayes and DuBuy, 1964). Oxytetracycline was deposited mainly in the shell (0.182 ± 0.028 iig./gm., mean ± SD), and albumen (0.190 ± 0.030 !*g./gm.) whereas the yolk contained ...

This research is aimed to improve the oxytetracycline production from Streptomyces rimosus. Five relatively high oxytetracycline yielding strains were obtained by nitrosoguanidine mutation of the protoplast of initial oxytetracycline producing strain Streptomyces rimosus JH and then subjected to genome shuffling as parental strains. The protoplasts of the five parental strains were prepared and...

OBJECTIVES In this study we examined the in vitro synergistic effect of baicalin, the flavone constituent of Scutellaria spp., in combinations with oxytetracycline and tetracycline on the growth of Staphylococcus aureus. METHODS The MICs were determined by the broth microdilution method and the effect of combinations was evaluated according to the sum of fractional inhibitory concentration in...

In this study, a simple, sensitive, selective and precise HPLC method is developed for the determination of oxytetracycline in bulk and honey samples. Separation of oxytetracycline was achieved on a Kromosil C18 analytical column (250 mm × 4.6 mm I.D., 5 μm particle size). The mobile phase was a mixture of acetonitrile and water (85:15 v/v) at a flow rate of 1.5 ml/min. The method was linear in...

Many farmers in developing countries protect their crops with oxytetracycline and fertilize their farmlands with manure from animals that received this drug as growth promoter. In this study, a tropical soil was exposed to 0.1 mg kg(-1), 1 mg kg(-1), and 10 mg kg(-1) of oxytetracycline for 22 days to evaluate whether this antibiotic alters the capacity of a soil microbial community to metaboliz...