OBJECTIVES The Japanese Veterinary Antimicrobial Resistance Monitoring (JVARM) Program was established in 1999 to examine the susceptibility of bacteria from food-producing animals to antimicrobial agents. This study tested the susceptibility of Salmonella isolates collected during 2001-2002 to 20 antimicrobials. MATERIALS AND METHODS MICs of antimicrobial agents were determined using the NCC...

Folsomia candida Willem (Isotomidae: Collembola) is an edaphic parthenogenetic species commonly used in ecotoxicity studies. We exposed F. candida to a high dose of three antibiotics, tylosin, ampicillin, and oxytetracycline, that target different bacterial groups. Possible toxic effects were assessed through egg production, hatching, and body size. All three antibiotics caused toxic effects. ...

American foulbrood (AFB) and European foulbrood (EFB) are destructive, infectious bacterial diseases in honeybees (Apis melifera), which can severely decrease the honey bee population and honey production (Gojmerac, 1980). American foulbrood spores are highly-resistant and can remain vital in combs and honey for many years. To control outbreaks of these infections in honeybee colonies, tetracyc...

The practice of antimicrobial usage in African catfish (Clarias gariepenius) production and the presence of antimicrobial residue in catfish in Oyo State were investigated by cross sectional study. Twenty commercial fish farmers were interviewed using interviewers administered semi-structured questionnaire on the pattern of antibiotic usage, knowledge of occurrence and risks of antimicrobial re...

Thirty-five patients with ocular rosacea were admitted to a trial of systemic oxytetracycline, 250 mg b.d. for 6 weeks. Oxytetracycline produced a significantly higher number of remissions than the placebo, 11/35. With repeated or continuous treatment 19/35 patients achieved a sustained remission for 8 months. There were no side effects. The nonspecific signs of ocular rosacea responded well to...

Antibiotics, particularly oxytetracycline, have been discussed as a possible predisposing condition in the appearance of chalkbrood in the honeybee (Apis mellifera L.). Nevertheless, the scientific data to support this belief have been insufficient. We have developed a method to study the effects of this antibiotic as a predisposing factor under different circumstances. We conclude that oxytetr...

In breast cancer treatment, chemotherapy resistance is a major problem where many receptive tumors rebound and develop resistance. When provided in combination, drugs are most successful, thus reducing the risk of developing resistant cells. However, evaluation combination therapies has increased rapidly recent years. Consequently, by repurposing old treatments, discovery additional medicines t...

The aim of the study was to compare the effects of stress (contamination trials) on the microorganisms in zinc-polluted soil (5,018 mg Zn kg(-1) soil dry weight) and unpolluted soil (141 mg Zn kg(-1) soil dw), measured as soil respiration rate. In the laboratory, soils were subjected to copper contamination (0, 500, 1,500 and 4,500 mg kg(-1) soil dw), and then a bactericide (oxytetracycline) co...

The in vitro activities of aivlosin tylosin tiamulin, erythromycin, oxytetracycline, spectinomycin, lincomycin, lincomycin-spectinomycin (1:2) and enrofloxacin were determined against twenty-eight isolates of Mycoplasma gallisepticum and 4 isolates of Mycoplasma synoviae using microbroth dilution method. The isolates showed various susceptibilities to antimicrobial agents. Aivlosin, lincomycin-...

BACKGROUND Mycoplasma mycoides subspecies mycoides Small Colony (MmmSC) is the causative agent of Contagious Bovine Pleuropneumonia (CBPP), a disease of substantial economic importance in sub-Saharan Africa. Failure of vaccination to curtail spread of this disease has led to calls for evaluation of the role of antimicrobials in CBPP control. Three major classes of antimicrobial are effective ag...