Pathergy phenomenon is defined as a state of altered tissue reactivity that occurs in response to minor trauma. Pathergy test (PT) is an easy to perform skin test to look for the pathergy phenomenon. This test is used as a criterion in most diagnostic criteria for Behcet’s disease e.g., Dilsen criteria, Japan revised criteria, International criteria, Iran traditional format criteria, and the Cl...

OBJECTIVES To assess the effect of surgical cleaning of the skin on the pathergy phenomenon in Behçet's syndrome. METHODS The pathergy phenomenon was assessed in 183 patients with Behçet's syndrome in a single blind study at 48 hours after a needle prick of the forearm skin, cleaned in the conventional way with alcohol, with 10% povidine iodine, with 100% chlorhexidine, and with a 4% aqueous ...

the pathergy phenomenon (pp) is one of the hallmarks of behcet's disease (bd). it has been reported to be positive from 17.5% to 83% of cases in different studies. pp is used as a diagnosis criterion in the dilsen criteria, the japan criteria, the international criteria, and the iran criteria. it is therefore important to know wether pp is a fix manifestation of the disease or a cyclic manifest...

the skin hyperreactivity, detected by the pathergy test, is a well known phenomenon in behcet's disease. two different methods were used for the pathergy test. a) a needle prick, b) an intadermal injection of normal saline. in this study 83% of behcet's patients had a positive pathergy test. where as 44% was of pustule type and 39% of papule type. in 26% of patients the papule formati...

OBJECTIVE Crohn's disease (CD) and ulcerative colitis (UC) share common clinical features with Behçet's syndrome (BS). We surveyed UC and CD patients for pathergy phenomenon and features of BS with the aim of determining how much overlap is present between these 2 entities in a setting where BS is relatively common, the frequency of pathergy positivity in inflammatory bowel disease (IBD) patien...

, 81 infliximab naive RA patients and 47 healthy subjects as controls. At the same time and apart from the purposes of that study, we also had done a pathergy test in those subjects who agreed to participate, with the aim of determining the effect of the pathergy phenomenon on the response of BS patients to the tuberculin test. Informed consent was obtained from all subjects. The study was appr...

We report the case of a 54-year-old woman with concurrent Sweet's syndrome, pathergy phenomenon and eythema nodosum-like lesions associated with suppurative tonsillitis. Tender, violaceous and highly edematous papules and plaques were detected on the forearms and legs, some of which were pseudovesicular. Similar edematous papules were detected on the dorsum of the hands at the sites of intraven...