chlamydia pneumoniae is a common respiratory pathogen which is often found in our paediatric populations. many patients with community-acquired pneumonia caused by c. pneumoniae have symptoms suggestive of sinusitis.the role of c. pneumonia in rhinosinusiits children (meanage =4.3 ±2.5year). this case control study was done in the pediatric and ent clinics of hazrat rasul hospital in tehran (20...

Leishmaniases are vector-borne infections caused by protozoa of genus Leishmania, affecting various mammals, mainly carnivores and humans. Clinical patent disease is relatively easy to be diagnosed and laboratory-confirmed by direct detection of the parasite in clinical samples. However, in subclinical cases detection of the causative agent is possible by highly sensitive diagnostic techniques ...

Whiplash PCR, a reaction in which hairpin DNA structures are extended by poly-merase, is a useful method for DNA computing. For example, state transitions can be implemented by this method. However, the feasibility of using whiplash PCR in a speciic DNA algorithm should be carefully considered. We have implemented a general-purpose simulator to aid those who design protocols and algorithms for ...

introduction: reverse transcriptase-polymerase chain reaction (rt-pcr) assay is a useful tool for the detection of fusion transcript resulting from specific chromosomal translocation of the leukemia cells. a specific chromosomal abnormality, the philadelphia chromosome (ph), is present in 90% to 95% of cml patients.the aberration results from a reciprocal translocation between chromosome 9 and ...

Increasing numbers of alterations have been found in protooncogenes (e.g., ras, mir), as well as tumor suppressor genes (e.g., p53, Rb) in various types of tumors. The multiple mutations cannot be explained by the spontaneous mutation rate. It has been suggested that mutator phenotypes leading to the accumulation of these mutations may be required in the early stages of tumorigenesis. To test t...

background: adult worms of orientobilharzia turkestanicum live in the portal veins, or intestinal veins of cattle, sheep, goat and many other mammals caus-ing orientobilharziasis. orientobilharziasis causes significant economic losses to livestock industry of iran. however, there is limited information about genotypes of o. turkestanicum in iran. methods: in this study, 30 isolates of o. turkes...

OBJECTIVE Podophyllotoxin (PTOX), a natural compound in numerous plants, contains remarkable biological properties that include anti-tumor, anti-viral such as anti-human im- munodeficiency virus (HIV) activities. In order to avoid its adverse effects, various com- pounds have been derived from PTOX. 6-methoxy PTOX (MPTOX) is one of the natural PTOX derivatives with an extra methoxy group. MPTOX...

BACKGROUND The pathogenesis of osteoarthritis is related to abnormal mechanical stresses that alter cartilage metabolism and chondrocyte survival. Among the mechanical stresses, shear stress is held responsible for the development of arthritis. METHODS Monolayer cultures of human osteoarthritic chondrocytes were subjected to fluid-induced shear stress in vitro. A cDNA microarray technology wa...