Parkinson's disease is one of the most common neurodegenerative disorders. There are many documents about the effects of oxidative stress in Parkinson's disease etiology. Angiotensin II activates NADPH dependent oxidases and causes superoxides formation. Peganum harmala L. extract, which has angiotensin converting enzyme (ACE) inhibitory effect, is considered to evaluate oxidative stress inhibi...

Peganum harmala and Piper longum medicinal herbs are used in traditional medicine to treat various diseases and to relieve tragic processes. The chemical composition of these two compounds is their analgesic agent. The purpose of this study was the Peganum harmala and Piper longum rubbing oil effect on pain in male mice by using formalin test. In this study, male mice were divided into three gr...

Introduction: Benign prostatic hyperplasia (BPH) is considered as a major cause of lower urinary tract symptoms (LUTS) in older men and its most common sign is nocturia. Objectives: This study aimed to determine the effect of the seeds of Peganum harmala compared with tamsulosin on alleviating urinary symptoms in patients with BPH. Patients and Methods: In this single blind clinical trial study...

OBJECTIVE Peganum harmala (P. harmala), "Espand" in Persian, has small seeds and has been used in traditional medicine as emmenagogue and an abortifacient. It has various pharmacological effects such as antifungal, antibacterial, hypothermic, anticancer, antinociceptive, and reversible monoamine oxidase inhibition. CASE DETAILS This case was a 45 years old woman who ingested about 50 grams se...

Peganum harmala L. (Zygophyllaceae) is one of the most famous medicinal plants used in traditional medicine of Iran. The aim of this study was to consider antibacterial effects of the methanolic extract of different parts of P. harmala including root, stem, leaf, flower and seed against some important human pathogenic bacteria. Antibacterial properties of methanolic extract of mentioned parts w...

The statistical analysis revealed that 10g and 20g extracts of all the tested plants significantly inhibited the growth of Lemna minor with significant differences. The plants means were non-significant while the interaction between extracts and plants was significant. Fagonia cretica, Peganum harmala, Tribulus terrestris, Chrozophora tinctoria and Ricinus communis caused significant growth inh...

Parasites of the genus Leishmania are transmitted by sandflies that ingest the parasite in the amastigote stage resident within macrophages, then inoculate the promastigote stage into other hosts. Peganum harmala, or Syrian Rue, has pharmacologically active compounds including several alkaloids with antiprotozoal properties, which are found especially in the seeds and the roots. In this researc...

IN VITRO EVALUTION OF ANTIMICROBIAL EFFECTS METHANOLIC AND ACETONE EXTRACTS PEGANUM HARMALA LAVANDULA ANGUSTIFOLIA AGAINST SOME HUMAN PATHOGENIC MICROORGANISM

Theileria annulata, a protozoan parasite of cattle and domestic buffaloes, is transmitted by ticks of the genus Hyalomma, and causes a disease named Mediterranean or tropical theileriosis. In this research 50 cattle naturally infected with Theileria annulata were treated with the extract of the plant Peganum harmala. The treatment was continued for 5 days, the dose of the extract being 5 mg/kg ...