Pharmacogenetics research has advanced our knowledge of the genetic basis of individual drug responses. Further benefits stem from the translation of pharmacogenetics research into the clinic to identify patients who are at high risk of adverse drug events. However, American Indian and Alaska Native (AI/AN) populations have not benefited markedly from genetics-guided therapeutics. A key strateg...

Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder, primarily characterized by decrease in insulin secretion and typically accompanied resistance. When untreated, T2DM leading to an inevitable long-term complication. However, the novel treatment of like for example Glucagon-like Peptide-1 receptor agonists (GLP-1 RAs) give new perspectives patients achieve better glycemic control a...

OBJECTIVE Biomedical databases summarize current scientific knowledge, but they generally require years of laborious curation effort to build, focusing on identifying pertinent literature and data in the voluminous biomedical literature. It is difficult to manually extract useful information embedded in the large volumes of literature, and automated intelligent text analysis tools are becoming ...