نتایج جستجو برای: plaque inflammation

تعداد نتایج: 203595  

Objective(s): Cardiovascular disease is a leading cause of morbimortality with over half cardiovascular events occurring in the asymptomatic population by traditional risk stratification. This preliminary study aimed to evaluate systemic plaque vulnerability in patients with prior Coronary Artery Disease (CAD) with a single Whole Body [FDG] PET-CT scan in terms of plaq...

Journal: :Nature Clinical Practice Cardiovascular Medicine 2008

Journal: :Journal of Internal Medicine 2015

Journal: :Journal of the American College of Cardiology 2006

2015
Jun Tang Mark E. Lobatto Laurien Hassing Susanne van der Staay Sarian M. van Rijs Claudia Calcagno Mounia S. Braza Samantha Baxter Francois Fay Brenda L. Sanchez-Gaytan Raphaël Duivenvoorden Hendrik B. Sager Yaritzy M. Astudillo Wei Leong Sarayu Ramachandran Gert Storm Carlos Pérez-Medina Thomas Reiner David P. Cormode Gustav J. Strijkers Erik S. G. Stroes Filip K. Swirski Matthias Nahrendorf Edward A. Fisher Zahi A. Fayad Willem J. M. Mulder

Inflammation drives atherosclerotic plaque progression and rupture, and is a compelling therapeutic target. Consequently, attenuating inflammation by reducing local macrophage accumulation is an appealing approach. This can potentially be accomplished by either blocking blood monocyte recruitment to the plaque or increasing macrophage apoptosis and emigration. Because macrophage proliferation w...

Journal: :iranian journal of diabetes and obesity 0
seid kazem razavi ratki mojgan kord seyed ali sadr bafghi nasim namiranian mohamad sobhan ardekani nader nouri-majalan

objective: atherosclerosis disease, inflammation and malnutrition have strong association with end stage renal disease (esrd). diabetes mellitus (dm) is the most commonly esrd causes. diabetic nephropathy (dn) could be associated with inflammation. type 2 diabetic patients with advanced nephropathy show the highest levels of inflammatory markers. this study was designed to determine the associa...

Journal: :Neurology 2014
Glen C Jickling Seemant Chaturvedi

Despite recent advances in medical and surgical treatments to prevent arterial stroke, the cerebrovascular burden of atherosclerosis remains high. Factors associated with a high risk for arterial stroke include stenosis .50% and ulcerated plaque. Given the important role of inflammation in atherosclerotic plaque progression and rupture, a measure of plaque inflammation may help stratify arteria...

2014
Ian C. Campbell Jonathan D. Suever Lucas H. Timmins Alessandro Veneziani Raymond P. Vito Renu Virmani John N. Oshinski W. Robert Taylor

OBJECTIVE Although plaque erosion causes approximately 40% of all coronary thrombi and disproportionally affects women more than men, its mechanism is not well understood. The role of tissue mechanics in plaque rupture and regulation of mechanosensitive inflammatory proteins is well established, but their role in plaque erosion is unknown. Given obvious differences in morphology between plaque ...

Kord, Mojgan , Nafisi Moghadam, Reza , Namiranian, Nasim , Nouri-Majalan, Nader , Razavi Ratki, Seid Kazem , Sadr Bafghi, Seyed Ali , Sobhan Ardekani, Mohamad ,

Objective: Atherosclerosis disease, inflammation and malnutrition have strong association with end stage renal disease (ESRD). Diabetes mellitus (DM) is the most commonly ESRD causes. Diabetic nephropathy (DN) could be associated with inflammation. Type 2 diabetic patients with advanced nephropathy show the highest levels of inflammatory markers. This study was designed to determine the associa...

Journal: :Journal of internal medicine 2015
G K Hansson P Libby I Tabas

Atherosclerosis is a maladaptive, nonresolving chronic inflammatory disease that occurs at sites of blood flow disturbance. The disease usually remains silent until a breakdown of integrity at the arterial surface triggers the formation of a thrombus. By occluding the lumen, the thrombus or emboli detaching from it elicits ischaemic symptoms that may be life-threatening. Two types of surface da...

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