Journal:
:basic and clinical cancer research
0
maryam abdollahzadeh cancer research center, cancer institute, tehran university of medical sciences, tehran, iran
maryam beigom mobasheri medical genetics department, faculty of medicine, tehran university of medical sciences, tehran, iran, cancer research center, cancer institute, tehran university of medical sciences, tehran, iran
homayoun moslehi department of dermatology, razi hospital, tehran university of medical sciences, tehran, iran
mohammad hossein modarressi medical genetics department, faculty of medicine, tehran university of medical sciences, tehran, iran
objective: basal cell carcinoma (bcc) is the most common human malignant neoplasm which is more frequent in white individuals. ptch and p53 are two major tumor suppressor genes which play important roles in pathogenesis of bcc. ptch is a twelve-pass transmembrane protein. it is an essential component of the sonic hedgehog signaling pathway that plays as a receiving receptor for members of the h...
