migraine involves 5-10% of children and adolescents. thirty percent of children with severe migraine attacks have school absence and reduced quality of life that need preventive therapy. the purpose of this randomised control trial study is to compare the effectiveness, safety and the tolerability of pregabalin toward propranolol in migraine prophylaxis of children. from may 2011 to october 201...

objectives: acute pancreatitis is an inflammatory condition of pancreas with sudden onset, high mortality rate and multiple organ failure characteristics. it has been shown that oxygen free radicals have an important role in development of pancreatitis and its complications. antioxidant, anti-inflammatory, anti-hepatotoxicity and gastroprotective properties of cichorium intybus l. suggest that ...

Sir, I read with interest the recent report of acute myopia induced by topiramate used for migraine prophylaxis. I would like to make certain observations. Firstly, Bhattacharyya et al used two medications (flunarizine and topiramate) as the initial preventive treatment of migraine. However, the guidelines recommend usage of a single drug. The drug should be considered a failure only after an a...

evidence acquisition medline, pubmed, ovid and embase were used to search for clinical studies comparing with or without prophylactic use of lamivudine for hbv reactivation in breast cancer patients receiving chemotherapy. outcomes of interest were the rate of hbv reactivation, incidence of hepatitis and incidence of hepatitis attributable to hbv reactivation, severity of hepatitis and severity...

background: acute pancreatitis (ap) refers to afflicted inflammation of pancreas with unfavorable adverse effects and developed multiple organ failures. unfortunately, there is not a certain therapeutic method for this disease. oxidative stress has a serious role in the pathogenesis of ap. thus, decreasing of oxidative stress may prevent induction and progression of ap. punica granatum l. has b...