magnetic force microscope ( mfm ) is a powerful technique for mapping the magnetic force gradient above the sample surface. herein, single-wall carbon nanotubes (swcnt) were used to fabricate mfm probe by dielectrophoresis method which is a reproducible and cost-effective technique. the effect of induced voltage on the deposition manner of carbon nanotubes (cnt) on the atomic force microscope (...

Arrayed Ti6Al4V nanotubes (TNT) coated with hydroxyapatite (HA) were synthesized via electrochemical anodization method. Paracetamol was loaded onto TNT-HA electrode. Effects of anodization, nanotube formation and hydroxyapatite deposition on sorption and release of the drug were investigated. Saturation time of paracetamol on the anodized samples was 30% shorter than the hydroxyapatite-coated ...

Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...

Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...

background: cyp2d6 is polymorphically expressed enzyme that show marked interindividual and interethnic variation. phenotyping of cyp2d6 provides valuable information about real-time activity of this important drug-metabolizing enzymes through the use of specific probe drugs. the aim of this study was to identify the cyp2d6 oxidation phenotype with dextromethorphan (dex) as a probe drug in maza...

Drug resistance (especially multiple drug resistance) in Mycobacterium tuberculosis makes global concerns in treatment and control of tuberculosis. Rapid diagnosis of drug resistant strains of the bacteria has vital importance in the prognosis of the disease. The aim of this study was to identify the mutations responsible for drug resistance in Mycobacterium tuberculosis strains derived from pa...

Background: CYP2D6 is polymorphically expressed enzyme that show marked interindividual and interethnic variation. Phenotyping of CYP2D6 provides valuable information about real-time activity of this important drug-metabolizing enzymes through the use of specific probe drugs. The aim of this study was to identify the CYP2D6 oxidation phenotype with dextromethorphan (DEX) as a probe drug in Maza...