Prostate cancer is the most common and second leading cause of death among men in the world. Nowadays, radiotherapy has been known as one of the most affecting methods for prostate cancer treatment. Nevertheless, radiotherapy is accompanied by the concern of developing secondary cancers by the scattered radiation to the neighbor  organs at risk. Several studies have shown that secondary cancers...

ionization radiation caused to incidence of complications in the exposed organs. in prostate radiotherapy, rectum and bladder have been radiated unwantedly and indicated some complications during and after treatment. the purpose of present study is to consider and to compare clinical complications of rectum and bladder in custom block and mlc for 3- d conformal radiotherapy, in order to determi...

Background: Based on the radiation biology model of prostate cancer, hypofractionated radiotherapy can improve the treatment outcomes without increasing toxicity. Although hypofractionated radiotherapy is implemented over a short period of time, it is more convenient and cheaper compared with conventional fractionated treatment. The aim of this study was to investigate the early toxicity of mod...

best treatment option, although, there is no common consent on optimal therapy for advanced prostate cancer. case presentation: the present study reports a case of 75 year-old man who had a huge heterogeneous soft tissue mass lesion with non-homogeneous enhancement consisted low attenuated foci occupying pelvis cavity and lower abdomen with loss of mesenteric fat and invasion to posterior bladd...

introduction accurate estimation of the skin-absorbed dose in external radiation therapy is essential to estimating the probability of secondary carcinogenesis induction materials and methods electron contamination in prostate radiotherapy was investigated using the monte carlo (mc) code calculation. in addition, field size dependence of the skin dose was assessed. excess cancer risk induced by...

background : safe dose escalation is highly desirable in radiotherapy for prostate cancer. prostate displacement due to bladder filling can be significant, so improved targeting of the prostate by ultrasound imaging potentially allows for a reduction in the target margin and consequently less toxicity. this study estimates the accuracy of ultrasound for prostate and bladder volume measurements ...

Introduction: The close proximity of the rectum tissue to the prostate gland results in rectal toxicity during prostate radiotherapy. Rectal Retractor (RR) is a rectal displacement technique that inserts into the rectum, as a result, the lateral and dorsal part of the rectal wall push away from high dose areas. The aim of this study was to investigate the dosimetric consequence...

background: for the purpose of individual clinical target volume assessment in radiotherapy of prostate cancer, mrsi was used as a molecular imaging modality with mri and ct images. materials and methods: the images of 20 prostate cancer patients were used in this study. the mr and mrsi images were registered with ct ones using non-rigid registration technique. the ct based planning (bp), ct/mr...

background: to evaluate the dosimetric difference between conventional and three-dimensional conformal radiotherapy (3d-crt) using 6 and 18 mv x-ray photons. materials and methods: computed tomography scans of 26 pelvic patients were acquired and transferred to the 3d treatment planning system. for each patient, 8 conventional plans (3, 4, 5 and 6 fields) and one 3d-crt plan were prepared using...

OBJECTIVES To assess the use of post-salvage radiotherapy prostate-specific antigen for early prediction of biochemical failure or clinical recurrence after salvage radiotherapy in recurrent prostate cancer patients after prostatectomy. METHODS From 2000 to 2011, 164 patients were treated with salvage radiotherapy alone for recurrent prostate cancer. Patients who received androgen deprivation...