We present cases of primary open angle glaucoma patients without previous history of pseudoexfoliation who developed pseudoexfoliative materials on the anterior surface of the intraocular lens after cataract surgery. Among 5 unilateral pseudophakic pseudoexfoliation cases, 3 showed a more advanced state of glaucoma in the affected eye. The other 2 cases showed progression of glaucoma in the aff...

Pseudoexfoliation syndrome is an agerelated disease characterized by the pathological production and accumulation of an abnormal extracellular fibrillar material over ocular tissues as well as other tissues and organs in the body such as the lung, liver, kidney, gall bladder, and cerebral meninges. The specific pathogenesis of pseudoexfoliation syndrome and the exact chemical composition of the...

The presence of pseudoexfoliation material on the surface of an intraocular lens (IOL) is a rare finding. We report a series of seven cases with different patterns of pseudoexfoliation material deposition on the posterior chamber IOLs, recognized 2-20 years after cataract surgery. Six patients had an IOL implanted in the capsular bag and one in the ciliary sulcus. Two patients had undergone pos...

The purpose of this study was to assess the prevalence of pseudoexfoliation syndrome and pseudoexfoliation glaucoma and to evaluate its association with open-angle glaucoma in patients attending the Department of Ophthalmology, Dr Tomislav Bardek General Hospital in Koprivnica, northwestern Croatia. This prospective study was conducted at Dr Tomislav Bardek General Hospital between December 201...

PURPOSE Pseudoexfoliation syndrome is a major risk factor for the development of glaucoma. Following recent reports of a strong association of coding variants in the lysyl oxidase-like 1 (LOXL1) gene with this syndrome but low penetrance and variable disease frequency between different populations, we aimed to identify additional genetic factors contributing to the disease. The clusterin (CLU) ...

Fluorescein iris angiography and fluorophotometry were performed on a series of 9 patients with bilateral and 11 with unilateral pseudoexfoliation, 12 bilateral aphakes with pseudoexfoliation, and 7 unilateral aphakes with bilateral pseudoexfoliation. Angiography showed a loss of radial iris vessels, a heavy leak of fluorescein from the pupil margin, progressive neovascularisation of the outer ...

Pseudoexfoliation (PEX) syndrome is an age-related systemic disease with primarily ocular manifestations characterized by deposition of whitish-gray pseudoexfoliation fibrillogranular amyloid like material on the anterior lens capsule, zonules, ciliary body, pupillary margin of the iris, corneal endothelium, anterior vitreous and trabecular meshwork [1,2]. The most important and easily recogniz...

Pseudoexfoliation syndrome (PES) is a systemic disorder caused by progressive accumulation of extracellular material over various tissues. PES usually determines increased intraocular pressure, changes in the anatomical aspects of the optic nerve, and visual field alterations leading to the diagnosis of pseudoexfoliation glaucoma (PEG). Use of topical medical treatment usually leads to poor res...

It is a matter of considerable clinical interest whether removal of the lens causes regression of pseudoexfoliation of the lens capsule. Before the paper by Dvorak-Theobald (I954), pseudoexfoliation of the lens capsule was often confused with true exfoliation, and it was suggested that lens extraction caused the condition to disappear (Irvine, I940; Gradle and Sugar, I947). After this paper app...