AIM To investigate the chemical interaction of calcium hydroxide with the antibiotics demeclocycline calcium in Ledermix Paste and clindamycin hydrochloride in Odontopaste. METHODOLOGY Validated methods were developed to analyse the interaction of calcium hydroxide in two forms, Pulpdent and calcium hydroxide powder, with the two antibiotics. High-performance liquid chromatography (HPLC) was ...

AIM To investigate the chemical interaction of calcium hydroxide with the corticosteroid triamcinolone acetonide in Ledermix Paste and in Odontopaste, a new steroid/antibiotic paste. METHODOLOGY Validated methods were developed to analyse the interaction of calcium hydroxide in two forms, Pulpdent Paste and calcium hydroxide powder, with triamcinolone acetonide within Odontopaste and Ledermix...

The aim of this study was to investigate whether differences in the composition of calcium hydroxide (Ca(OH)2) preparations influence the removal efficiency of irrigation solutions used in combination with filing of the canal. Three Ca(OH)2 preparations were used: Calxyl, Pulpdent paste, and chemically pure Ca(OH)2 mixed with distilled water. Fifty-one single-rooted extracted human teeth were p...

introduction: ca(oh) 2 -containing/forming materials are conventionally used for indirect pulp-capping and are theoretically able to release ca 2+ and oh - ions for hydrolytic dissociation. however, no evidence exists for ion diffusion through the remaining coronal dentin. the aim of this study was to design an innovative experimental set-up to test the ability of ca(oh) 2 -containing and ca(oh...

INTRODUCTION The aim of this study was to evaluate the cytotoxicity of a new nano zinc-oxide eugenol (NZOE) sealer in comparison with AH-26 and Pulpdent root canal sealers. METHODS AND MATERIALS The L929 mouse fibroblast cells were cultivated and incubated for 24, 48 or 72 h with different dilutions (1/1, 1/2, 1/4, 1/8, 1/16 and 1/32) of culture media previously exposed to either of the test ...

Introduction Hydroxyl ion release from calcium hydroxide is responsible for the key attributes of broad spectrum antimicrobial activity, penetration into biofilms, inhibition of endotoxins, and dissolution of organic tissues.1,2 The maximum solubility of calcium hydroxide in water at 25C is only 0.159 g/100mL (0.16%), and this reduces to 0.140 g/100 mL (0.14%) at 40C, with an accompanying decre...

INTRODUCTION The aim of this in vitro study was to evaluate the cytotoxicity of a new nano zinc-oxide eugenol (NZOE) sealer on human gingival fibroblasts (HGFs) compared with Pulpdent (micro-sized ZOE sealer) and AH-26 (resin-based sealer). METHODS AND MATERIALS The Pulpdent, AH-26, and NZOE sealers were prepared and exposed to cell culture media immediately after setting, and 24 h and one we...

OBJECTIVES The objective of this in vitro study was to evaluate and compare the cytotoxicity of four different root canal sealers i.e. Apexit Plus (Ivoclar Vivadent), Endomethasone N (Septodont), AH-26 (Dentsply) and Pulpdent Root Canal Sealer (Pulpdent), on a mouse fibroblast cell line (L929). MATERIALS AND METHODS Thirty two discs for each sealer (5 mm in diameter and 2 mm in height) were f...

AIM To evaluate the outcome of root canal treatment in primary teeth using three root canal filling materials - RC Fill, Vitapex and Pulpdent root canal sealer. METHODOLOGY The study was a single-centre, double-blind, randomized controlled trial carried out on 129 primary mandibular molars with necrotic pulps or irreversible pulpitis in 4- to 9-year-old children. Participants were selected ba...

Introduction: This interventional in-vitro study aimed to evaluate the antimicrobial activity of a new Nano Zinc OxideEugenol (NZOE) sealer in comparison with AH26 and Pulpdent common root canal sealers against endodontic pathogens. Methods: The antimicrobial efficacy of three sealers(NZOE, AH26 and Pulpdent)  against Enterococcus faecalis (ATCC 29212), Escherichia coli (ATCC 25922), Streptococ...