objective(s) air pouch is a well-established inflammatory model in which fluid extravasations; leukocyte migration, angiogenesis and other parameters involved in the inflammatory response can be measured. in this study, the influence of gender on inflammatory parameters has been examined in the air pouch model. materials and methods to induce air pouch, adult male and female wistar rats were an...

Abstract. Prior to their use under future changing climate conditions, all hydrological models should be thoroughly evaluated regarding temporal transferability (application in different time periods) and extrapolation capacity beyond the range of known past conditions). This note presents a straightforward evaluation framework aimed at detecting potential undesirable dependencies models: robus...

Evaluating the impact of Viola spathulata in a rat model brain ischemia/reperfusion by influencing expression level caspase-3 and cyclooxygenase-2

The main objective of this study was to prepare colon-specific pellets of budesonide, using pectin as film coating. Pellet cores of budesonide were prepared by extrusion / spheronization technique. Pectin, in different ratios was combined with Eudragit RS30D, Eudragit NE30D or Surelease to produce film coating. The dissolution profiles of pectin coated pellets were investigated in pH of 1.2 (2 ...

The main objective of this study was to prepare colon-specific pellets of budesonide, using pectin as film coating. Pellet cores of budesonide were prepared by extrusion / spheronization technique. Pectin, in different ratios was combined with Eudragit RS30D, Eudragit NE30D or Surelease to produce film coating. The dissolution profiles of pectin coated pellets were investigated in pH of 1.2 (2 ...

Abstract The main objective of this study was to prepare colon-specific pellets of budesonide using pectin as film coating.  Pellet cores of budesonide were prepared by extrusion / spheronization technique. Pectin, in different ratios was combined with Eudragit RS30D, Eudragit NE30D or Surelease to produce film coating. The dissolution profiles of pectin coated pellets were investigated in pH o...

The journal retracts the following article: “Efficacy of Mesenchymal Stem Cell and Vitamin D in Treatment Diabetes Mellitus Induced a Rat Model: Pancreatic Tissues [...]

Cisplatin is an effective chemotherapeutics against a wide range of cancers. However, it causes significant nausea and vomiting which limit its usefulness. In the present study, the effects of methanolic root extract of Pluchea lanceolata (DC.) C. B. Clarke , asteraceae ( MPL ) was investigated against cisplatin-induced nausea using a rat pica model. In rat pica model, rats react to cispla...