Cashmere is only produced from Maraz (Kurdi) goat breed in Iraqi Kurdistan Region. The objective of this study was to assess the genetic diversity of different Maraz color types, black goat and Shami breeds using random amplified polymorphic DNA (RAPD) markers. Fourteen primers were used and nine out of them were selected based on their number of bands (NB) and polymorphic characteristics. Thes...

p70 ribosomal S6 kinase (p70S6K) can integrate nutrient and growth factor signals to promote cell growth and survival. We report our molecular characterization of the complementary DNA (cDNA) that encodes the goat p70S6K gene 40S ribosomal S6 kinase 1 (S6K1) (GenBank accession GU144017) and its 3' noncoding sequence in Inner Mongolia Cashmere goats (Capra hircus). Goat S6K1 cDNA was 2,272 bp an...

Fiber diameter, a quantitative trait, is controlled by minor effect polygenes. Keratin-associated proteins (KRTAPs) are an important part of hair, and their rich polymorphisms facilitate the mining cashmere trait molecular markers. In this study, Jiangnan Tibetan goats were taken as research object; multiplex PCR exome sequencing technology used to identify exon regional KRTAP15-1, KRTAP13.1, K...

One hundred eighty (180) skin samples were taken from the mid-right side of 30 Raieni Cashmere goat male and female kids at 1 mo, 1.5 mo, 2 mo, 2.5 mo, 3 mo and 3.5 mo of age. Numbers of primary and secondary skin follicles were determined for each sample. Numbers of secondary follicles increased until 3 mo of age, but numbers of primary follicles did not change after birth of the kids. The ski...

Cashmere goat skin contains two types of hair follicles (HF): primary hair follicles (PHF) and secondary hair follicles (SHF). Although multiple genetic determinants associated with HF formation have been identified, the molecules that determine the independent morphogenesis of HF in cashmere goats remain elusive. The growth and development of SHF directly influence the quantity and quality of ...

Previous molecular genetic studies of the goat hair life cycle have focused primarily on a limited number of genes and proteins. To identify additional genes that may play important roles in hair follicle cycle regulation, Illumina sequencing technology was used to catalog differential gene expression profiles in the hair growth cycle (anagen to catagen) of goat, comparing the primary hair foll...

Pedigree information which collected from 1979 to 2012 were used to study the genetic variability and population structure of Raeini Cashmere goat, taking kids born from 2009 to 2012 into account as reference population. Averages of inbreeding coefficients in whole and inbred populations were computed to be 0.04% and 4.41%, respectively. Considering the reference population, average inbreeding ...

MicroRNAs (miRNAs) are a class of small RNAs that play significant roles in regulating the expression of the post-transcriptional skin and hair follicle gene. In recent years, extensive studies on these microRNAs have been carried out in mammals such as mice, rats, pigs and cattle. By comparison, the number of microRNAs that have been identified in goats is relatively low; and in particular, th...