objective: this study was designed to investigate rbc indices and hba2 levels in parents of major beta-thalassemia patients to detect possible silent beta- thalassemia carriers and examine its potential impact on the premarital genetic counseling. materials and methods: this cross sectional study was performed at children medical center from 2004 to 2006. after genetic counseling and getting in...

BACKGROUND & AIMS Red blood cell (RBC) indices have been demonstrated to be associated with fatty liver disease (FLD) and metabolic syndrome. However, controversy exists regarding the relationship of RBC indices with FLD to date and few has focused on RBC count. This study aimed to explore the association between RBC count and risk of FLD in Southern Chinese adults. METHODS A hospital-based c...

Materials and methods: Couples who intend to marry have to undergo these tests as part of a compulsory countrywide program. In this study, the red blood cell (RBC) indices among the study population were measured with an electronic cell counter (Sysmex K800). Th e survey involved the measurement of 2 RBC indices, mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH), and the resul...

AIM: To assess the validity and discrimination power of haemogram parameters and RBC indices in diagnosing βTT in microcytic, hypochromic anaemia. MATERIAL AND METHODS: A prospective study was conducted on the microcytic, hypochromic anaemic OPD and indoor admitted patients in Umaid Hospital, Jodhpur measured with electronic cell counter (Sysmex K800). HbA2 was calculated on the cohort by the H...

Red blood cells (RBC) and reticulocyte parameters were determined on peripheral blood from a subset of patients enrolled in the multicenter study of hydroxyuea (HU) in sickle cell anemia. Multiple blood samples were obtained every 2 weeks. Cellular indices were measured by flow cytometry. Generalized linear models were used to determine the relationship between the longitudinal trajectories of ...

Objective: Iron deficiency anemia (IDA) and beta-thalassemia trait (ß-TT) are the most common forms of microcytic anemia. This study was conducted to compare the validity of various discrimination indices in differentiating β-TT from IDA by calculating their sensitivity, specificity and Youden's index. Methods: Totally 323 subjects (173 children and 150 adults) with microcytic anemia were invol...

Multiwavelength transmission (MWT) spectroscopy was applied to the investigation of the morphological parameters and composition of red blood cells (RBCs). The MWT spectra were quantitatively analyzed with a Mie theory based interpretation model modified to incorporate the effects of the nonsphericity and orientation of RBCs. The MWT spectra of the healthy and anemic samples were investigated f...

INTRODUCTION Folate deficiency is assessed by serum and red blood cell folate measurements. Nevertheless, no consensus for the lower limit of serum folate reference values exists. We investigated the appropriate use of RBC folate to detect folate deficiency and the relationship between serum and RBC folate and with other parameters such as vitamin B12 and homocysteine in order to propose serum ...

The purpose of the study was to evaluate erythrocyte indices and platelet indices in dogs with leishmaniasis (CL, L. infantum). CL was diagnosed by polymerase chain reaction, and confirmed by western blott in 54 dogs. These dogs were divided into three groups; asymptomatic (n=16), oligosymptomatic (n=16), and symptomatic (n=22). Leishmaniasis free 25 dogs were served as controls. Microcytic or ...