background and objectives: presence of steroid hormone receptors (estrogen and progesterone) in the tumor tissues of various organs correlates with response to therapy and prognosis. since their role in ovarian cancer is still controversial, in this study we investigated the expression and prognostic value of the estrogen receptor (er) and progesterone receptors (pr) in ovarian papillary serous...

some lesions in the oral cavity and mostly on gingiva have predominant predilection towards females, and mostly occur in the first four decades of life when changes in sex hormone levels in blood are obvious. the present study aimed to investigate the presence and distribution of estrogen and progesterone receptors in peripheral giant cell granuloma (pgcg), pyogenic granuloma (pg) and periphera...

we have reviewed the medical records of 40 patients with disseminated (bacille calmette-guerin) bcg from 1996 to 1999 in the immunology department of the children hospital, medical center, tehran university. these patients are divided in to 3 groups: 1. patients who had disseminated (bacille calmette-guerin) bcg after vaccination and their diagnosis was chronic granulomatous disease. 2. patient...

objective(s): we aimed to examine association of gene expression of mor1 and glun1 at mrna level in the lumbosacral cord and midbrain with morphine tolerance in male wistar rats. materials and methods: analgesic effects of morphine administrated intraperitoneally at doses of 0.1, 1, 5 and 10 mg/kg were examined using a hot plate test in rats with and without a history of 15 days morphine (10 mg...

background: the etiology of breast cancer and our understanding on the carcinogenicity of different risk factors is impotant for control programms. objective: we investigated the expression of estrogen and progesterone receptors (er, pr), and human epithelial receptor 2 (her2) overexpression and its associations, with environmental risk factors among breast cancer patients.  methods: we classif...

background: papillary thyroid carcinoma (ptc), occurs mostly in women and sex hormones may play a role in the pathogenesis and clinical course. the objective of this study was to determine the status and prevalence of estrogen and progesterone receptors in ptc with regard to age, gender, tumor size and lymph node involvement. methods: immunohistochemical stains were performed on 92 tissue block...

background: premenstrual dysphoric disorder (pmdd) is a mood disorder characterized with physical and affective symptoms during the luteal phase of susceptible women. objective: the aim of this study was to investigate the association of dopamine d3 receptor ( drd3 ) polymorphism, and cannabinoid receptor type 1 ( cnr1 ) polymorphism with pmdd. materials and methods: fifty one participants with...

male breast cancer is a rare disease with an increasing trend. due to limited information especially about the genetic basis of the disease in iran and the lower age of its onset, the disease requires more attention. the aim of this study was to screen the male patients with breast cancer for brca mutations as well as tissue markers of estrogen receptor (er), progesterone receptor (pr), human e...

conclusions tlr8 rs3764880 and tlr9 rs148805533 polymorphisms may not be risk factors for susceptibility to tuberculosis in a sample of iranian population. larger studies are required to validate our findings. results the allelic and genotypic frequencies of the tlr8 rs3764880 did not differ significantly between ptb and the controls. no significant difference was found between the groups regar...