the aim of this study was to evaluate the morbidity and mortality in patients with operable stage ii and iii rectal cancers within one or two months after surgery, who has been treated pre-operatively with short course radiotherapy. twenty-eight patients with rectal adenocarcinoma, consecutively referred to the cancer institute of imam khomeini hospital from march 2009 to march 2010, were selec...

background: considering the ease of administration of capecitabne instead of infusional 5fu for concurrent  radiochemotherapy (rct) of rectal cancer, the use of capecitabine has increased significantly in our radiation oncology department in the past years. thus we decided to compare the safety and survival with these 2 drugs by a retrospective review. methods: files of all patients receiving r...

Middle rectal artery is one of the important arteries supplying the rectum, along with the superior and inferior rectal arteries. Study of middle rectal artery was undertaken as it is important in surgeries of rectal carcinoma. .For the present study 40 pelvises were procured from the department of Anatomy of Dr. D. Y. Patil Medical College, Pune.Variations were found in the origin of middle re...

This is a concise letter on the observation of patient with large bilateral asymmetric ulcerative cutaneous metastasis from rectal carcinoma.

cutaneous metastases of rectal carcinoma is a rare event. it occurs in fewer than 4% of all patients with rectal cancer. when present, it typically signifies a disseminated disease with a poor prognosis. early detection and proper diagnosis of metastatic rectal cancer can significantly alter treatment and prognosis. we report a 70-year-old male who underwent rectal resection with permanent colo...

Therapeutic strategies for colo-rectal relies on several parameters among which microsatellite (MS) and RAS/RAF status have important value. The aim of our study was to analyze combined MS in colorectal carcinoma (CCR). We a series 73 cases CCR with nodal/visceral metastasis. determined by immunohistochemistry. Molecular testing performed the RT-PCR automatized Idylla system. 67 were MS-profici...

An 87-year-old-man with prostate-cancer-stage-T1c-Gleason-6 treated with radiotherapy in 1996, recurrent prostate cancer treated with leuprolide hormonal therapy in 2009, and bladder-urothelial-carcinoma in situ treated with Bacillus-Calmette-Guerin and adriamycin in 2010, presented in 2015 with painless, bright red blood per rectum coating stools daily for 5 mo. Rectal examination revealed bri...

In order to relieve mechanical obstruction caused by rectal carcinoma, a bare rectal stent was inserted in the sigmoid colon of a 70-year-old female. The procedure was successful, and for one month the patient made good progress. She then complained of abdominal pain, however, and plain radiographs of the chest and abdomen revealed the presence of free gas in the subdiaphragmatic area. Surgical...

A rectal carcinoma, including primary an adenosquamous and a squamous cell carcinoma (SCC), is a very rare disease, accounting for 0.025% to 0.20% of all large-bowel malignant tumors. Because SCCs have a higher mortality than adenosquamous carcinomas, determining whether the primary rectal cancer exhibits an adenomatous component or a squamous component is important. While differentiating betwe...

BACKGROUND Mechanism of radioresistance in rectal carcinoma remains largely unknown. We aimed to evaluate the predictive role of ATP-binding cassette subfamily C member 4 (ABCC4) in locally advanced rectal carcinoma and explore possible molecular mechanisms by which ABCC4 confers the resistance to neoadjuvant radiotherapy. METHODS The expression of ABCC4 and P53 mutant in biopsy tissue specim...