introduction: breast cancers in the early phase frequently undergo distant metastasis and survival of patients is greatly dependent on distant metastasis. the occurrence of micrometastasis has been suggested to relate with prognostic features of breast cancer, such as lymph node metastasis and the presence of vascular invasion. the aim of this study was to examine the presence of keratin-19 mrn...

OBJECTIVE Relapse and acute exacerbation are common in schizophrenia and may impact treatment response and outcome. Evidence is conflicting in respect to superiority of long-acting injectable antipsychotic therapies versus oral antipsychotics in relapse prevention. This randomized controlled study assessed the efficacy of paliperidone palmitate versus oral antipsychotics for relapse prevention....

Background: Patients with Graves’ disease exhibit a considerable rate of relapse after treatment with antithyroid drugs and require ablative therapy. Objective: The purpose of this study was to evaluate variables which can be used as prognostic factors in predicting the outcome of Graves’ disease after treatment with antithyroid drugs. Methods: Age, sex, duration of antithyroid drug therapy, pr...

background: patients with graves’ disease exhibit a considerable rate of relapse after treatment with antithyroid drugs and require ablative therapy.   objective: the purpose of this study was to evaluate variables which can be used as prognostic factors in predicting the outcome of graves’ disease after treatment with antithyroid drugs.   methods: age, sex, duration of antithyroid drug therapy...

BACKGROUND A relapse prevention program called the Information Technology Aided Relapse Prevention Programme in Schizophrenia (ITAREPS) has been developed and is reported to be highly effective. However the effectiveness was influenced by user adherence to the protocol of the program, the exact effectiveness and the role of the ITAREPS have been partially uncertain. OBJECTIVE The purpose of t...

conclusions in the initial treatment, it seems necessary to supervise and monitor the treatment process through staff in addiction treatment centers together with the company of the addicts’ families to reduce relapse rate. results the relapse rate was 30.42%, mean and median of the time to relapse (survival time) were 27.40 ± 1.63 months (ci 95%: 24.19 - 30.60) and 25 ± 2.25 months (ci 95%: 22...

acute leukemias represent approximately 30% of malignant diseases in patients under the age of 15 years. leukemic infiltration of the central nervous system and testis are common events, particularly as sites of relapse in the third year after diagnosis. management of acute lymphoblastic leukemia is based on long-term chemotherapy, leading to a cure rate of approximately 80% of children and ado...