the effect of oleic acid (5 and 10% v/v) and xanthan gum (0.5 and 1% wt) on  partitioning and retention of ethyl acetate and diacetyl from two matrices with a different composition was investigated by applying static head space gas chromatography. two matrices with different composition have been developed: one containing carbohydrates (xanthan gum) and in the second one, called complex matrix,...

introduction: tuberculosis (tb), with different types of respiratory tract involvements, has a high rate of mortality all around the world. endobronchial involvement, which is a slightly common tuberculous infection, requires special attention due to its severe complications such as bronchostenosis. aim of study of this study was describes, one type of pulmonary tuberculosis with less diagnosed...

the goal of this research is preparation, optimization and in-vitro evaluation of rifampin-loaded silica nanaoparticles in order to use in pulmonary drug delivery. nanoparticles are exhaled because of thier small size, preparation of nanoaggregates in micron-sized scale and re-disrpersion of them after the deposition in the lung is one approach in order to overcome this problem, which we used i...

despite existing various integer programming for sequencing problems, there is not enoughinformation about practical values of the models. this paper considers the problem of minimizing maximumlateness with release dates and presents four different mixed integer programming (mip) models to solve thisproblem. these models have been formulated for the classical single machine problem, namely sequ...

the objective of research was to explore the suitability of lipids like compritol 888 ato and stearic acid as release retardant to develop sustained release (sr) tablets. the sr micromatrices of lipid (s) and glipizide were prepared (lm1- lm6) as intermediate product by fusion method and assessed for various pharmacotechnical properties. micromatrices were formulated as sr tablets (f1-f6) by di...

context biocompatible polymers are potentially effective for dental infections as delivery carriers of disinfectants or antibiotics into the root canal system (rcs). this study aimed to review polymeric microspheres enabling a controlled release of endodontic medicaments. evidence acquisition a literature search was carried out in the pubmed database (may 2013) using the following keywords: “po...

objective(s): the quantitative calculation of release data is more facil when mathematics come to help. mathematically modeling could aid optimizing and amending the delivery systems design. aim of this study is to find out the isoniazid release kinetic. methods: in this work degradable temperature sensitive dextran-hydroxy ethyl methacrylate- poly-n-isopropyl acryl amide (dex-hema-pnipaam) nan...

it has been observed that most of the chemical entities have high lipophilicity and poor aqueous solubility, which result in poor bioavailability. in order to improve the bioavailability, the release behavior of such drugs should be improved. although there are numerous techniques to handle solubility related issue, but they are expensive due to involvement of complicated equipments, advanced m...

a controlled release matrix formulation for mesalamine was designed and developed to achieve a 24 h release profile. using compritol 888 ato (glyceryl behenate) as an inert matrix-forming agent to control the release of mesalamine, formulation granules containing the solid dispersions were investigated. pectin, a polysaccharide, was used as bacterial dependent polymer for colon targeting. the m...