The world is rapidly ageing. It is against this backdrop that there are increasing incidences of dementia reported worldwide, with Alzheimer's disease (AD) being the most common form of dementia in the elderly. It is estimated that AD affects almost 4 million people in the US, and costs the US economy more than 65 million dollars annually. There is currently no cure for AD but various therapeut...

The aim of this study was to investigate clinical and radiographic outcomes in patients 50 years and younger vs patients older than 50 years undergoing total ankle replacement. Seventy consecutive patients who underwent primary total ankle replacement were included in this retrospective study. Patients were assessed clinically and radiographically. There was a statistically significant differen...

We consider an age replacement problem with cost function based on the renewal reward theorem. However, instead of assuming a known probability distribution for the lifetimes, we apply Hill’s assumption A(n) for predicting probabilities for the lifetime of a future item. Lower and upper bounds for the survival function of a future item are used, resulting in upper and lower cost functions. Mini...

Many factors can explain the most important increase of human life expectancy during the XXth century: better socioeconomic conditions, improved working conditions, development of preventive measures, less alcoholism, appearance of antibiotics, advances in medical practices, etc... At present, the fastest growing age group in western countries is people >80 years old; they will represent 9–10.5...

the objective of this study was to determine the optimum replacement strategy using dynamic programming for dairy herds in fars province. a dairy cow is kept several lactations for milk production in the herd. after spending several lactations, milk production gradually begins to decline, while animal health problems rises simultaneously. so one of the most important management decisions of dai...