Linkage mapping of complex diseases is often followed by association studies between phenotypes and marker genotypes through use of case-control or family-based designs. Given fixed genotyping resources, it is important to know which study designs are the most efficient. To address this problem, we extended the likelihood-based method of Li et al., which assesses whether there is linkage disequ...

Background In order to meet the challenges presented by increasing demand and scarcity of resources, healthcare organizations are faced with difficult decisions related to resource allocation. Tools to facilitate evaluation and improvement of these processes could enable greater transparency and more optimal distribution of resources.   Methods The Resource Allocation Performance Assessment Too...

in this paper, a hybrid method for limited resource allocation and leveling in complex multi-stage, multi-product and multi-period production planning problems with aim of lot-size determination and total cost minimization has been proposed. this problem consists of multiple products with sequential production processes that are produced in different periods to meet the customers demand. by det...

in dea to obtain an efficient representation in ccr andbcc models for each dmu only one linear plan would be solved; however,it is possible in centralized resource allocation (cra) to solve allthe dmus by one linear planning. in this paper, models of centralizedresource allocation in input-oriented and in dynamic case will be offeredand by using dynamic sbm, the representation of dmus in each t...

objectives: the role of cognitive process for postural control was shown in dual task studies. however, there was no definite evidence how verbal instructions influence the allocation of attention to postural control. this study determined whether young and elderly adult are able to deliberately control the resource allocation when performing a sensorimotor and cognitive task simultaneously and...