BACKGROUND AND OBJECTIVES Mucormycoses are a group of invasive infections caused by filamentous fungi of the Mucoraceae family, with the rhinocerebral form of the disease being the most common in large case series. In the present paper we review the characteristics of the rhinocerebral form of the disease. EVIDENCE AND INFORMATION SOURCES The present review is based on the analysis of the cur...

BACKGROUND Rhinocerebral mucormycosis occurs in immunocompromised hosts with uncontrolled diabetes, solid organ transplants, and hematologic malignancies. Primary disease is in the paranasal sinuses but often progresses intracranially, via direct extension or angioinvasion. Rhinocerebral mucormycosis is rapidly fatal with a mortality rate of 85%, even when maximally treated with surgical debrid...

INTRODUCTION Rhinocerebral mycosis is a rapidly progressive fatal opportunistic infection, predominantly affecting people in an immunocompromised state. Aggressive surgical therapy, with repeated debridement in combination with intravenous amphotericin B can lead to a high rate of cure. AIM To determine the predictors of mortality in rhinocerebral mycosis. MATERIALS AND METHODS The demograp...

We successfully treated 3 consecutive patients who had nonneutropenic rhinocerebral zygomycosis, by use of subcutaneous granulocyte-macrophage colony-stimulating factor therapy combined with traditional surgical and medical treatment. All patients are currently free of disease. Granulocyte-macrophage colony-stimulating factor should be considered as adjuvant therapy for rhinocerebral zygomycosi...

INTRODUCTION No comprehensive reports have been published on epidemiological status of Rhinocerebral zygomycosis infections and its outcome in our population, Hence, the current study came to address epidemiological characteristics as well as clinical outcome of patients with Rhinocerebral zygomycosis infection referred to a referral hospital in Iran. METHODS This retrospective study was perf...

Infections are usually detected in diabetes mellitus. They may be divided into: common infections such as fungal infections, pulmonary tuberculosis, pneumonia, bacteraemia, urinary tract infections, and diabetic foot infections and specific infections. The latter occur almost exclusively in diabetes and include rhinocerebral mucormycosis, malignant external otitis, emphysematous pyelonephritis,...

Introduction Rhinocerebral mucormycosis is a rare life-threatening infection caused by fungi from the family of mucoraceae. Here we report a rare case of Rhinocerebral mucormycosis in a 67-year-old diabetic patient. Case Report A previously healthy 67-year-old male presented with swelling and pain over the left side of the face, deviation of the angle of the mouth to right side and drooling of ...

Invasive fungal infections are associated with morbidity and mortality in immunocompromised patients. Rhinocerebral region infections are mainly due to opportunistic fungal pathogens. Although Zygomycosis and Aspergillosis are two major causes of paranasal infections, reports of combined Mucormycosis and Aspergillosis infections of rhinocerebral region are limited. We report a case of fatal, co...