نتایج جستجو برای: rna editing

تعداد نتایج: 273016  

Journal: :iranian journal of parasitology 0
b kazemi department of biotechnology, school of medicine, shahid beheshti university of medical sciences, tehran, iran and cellular and molecular biology research center, shahid beheshti university of medical sciences, tehran, iran

leishmania is a protozoan parasite belonging to the family trypanosomatidae, which is found among 88 different countries. the parasite lives as an amastigote in vertebrate macro­phages and as a promastigote in the digestive tract of sand fly. it can be cultured in the laboratory us­ing appropriate culture media. although the sexual cycle of leishmania has not been observed during the promastigo...

Journal: :FEMS Microbiology Reviews 1999

2013
Wei-Hsuan Huang Chao-Neng Tseng Jen-Yang Tang Cheng-Hong Yang Shih-Shin Liang Hsueh-Wei Chang

RNA editing is vital to provide the RNA and protein complexity to regulate the gene expression. Correct RNA editing maintains the cell function and organism development. Imbalance of the RNA editing machinery may lead to diseases and cancers. Recently, RNA editing has been recognized as a target for drug discovery although few studies targeting RNA editing for disease and cancer therapy were re...

Journal: :Current Biology 1995

2016
Mizuho Ichinose Mamoru Sugita

RNA editing by cytidine (C) to uridine (U) conversions is widespread in plant mitochondria and chloroplasts. In some plant taxa, "reverse" U-to-C editing also occurs. However, to date, no instance of RNA editing has yet been reported in green algae and the complex thalloid liverworts. RNA editing may have evolved in early land plants 450 million years ago. However, in some plant species, includ...

Journal: :RNA 2013
Zhongshan Li Hindrike Bammann Mingshuang Li Hongyu Liang Zheng Yan Yi-Ping Phoebe Chen Min Zhao Philipp Khaitovich

Adenosine-to-inosine (A-to-I) substitutions are the most common type of RNA editing in mammals. A-to-I RNA editing is particularly widespread in the brain and is known to play important roles in neuronal functions. In this study we investigated RNA-editing changes during human brain development and maturation, as well as evolutionary conservation of RNA-editing patterns across primates. We used...

2018
Wei Tang

RNA editing is an important process involved in the modification of nucleotides in the transcripts of a large number of functional genes. RNA editing results in the restoration of conserved amino acid residues for protein function in plants. In this review, I only describe and discuss the identified RNA editing and the RNA editing associated regulation in chloroplast, including cytidine-to-urid...

2013
Stéphane Bentolila Julyun Oh Maureen R. Hanson Robert Bukowski

In flowering plants, mitochondrial and chloroplast mRNAs are edited by C-to-U base modification. In plant organelles, RNA editing appears to be generally a correcting mechanism that restores the proper function of the encoded product. Members of the Arabidopsis RNA editing-Interacting Protein (RIP) family have been recently shown to be essential components of the plant editing machinery. We rep...

2001
LARRY SIMPSON

RNA Editing RNA editing is a term used to describe a diverse set of phenomena in which mRNA, rRNA, and tRNA transcripts are modified in sequence after transcription. The types of RNA editing vary from uridine (U) or cytidine (C) insertions and deletions within coding regions of mitochondrial mRNAs to the substitution of specific C residues with U residues in plant mitochondrial mRNAs or the sub...

2015
Wenqin Wang Wei Zhang Yongrui Wu Pal Maliga Joachim Messing Xiu-Qing Li

RNA editing is the post-transcriptional conversion from C to U before translation, providing a unique feature in the regulation of gene expression. Here, we used a robust and efficient method based on RNA-seq from non-ribosomal total RNA to simultaneously measure chloroplast-gene expression and RNA editing efficiency in the Greater Duckweed, Spirodela polyrhiza, a species that provides a new re...

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