نتایج جستجو برای: rs4821481

تعداد نتایج: 4  

Journal: :iranian red crescent medical journal 0
effat asdadollahpour medical biotechnology research center, ashkezar branch, islamic azad university, ashkezar, yazd, ir iran maryam daneshpour cellular and molecular endocrine research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, tehran, ir iran bahareh sedaghati khayat cellular and molecular endocrine research center, research institute for endocrine sciences, shahid beheshti university of medical sciences, tehran, ir iran arsalan hashemiaghdam diabetes research center, endocrinology and metabolism clinical sciences institute, tehran university of medical sciences, tehran, ir iran mahsa mohammad amoli endocrinology and metabolism research center, endocrinology and metabolism clinical sciences institute, tehran university of medical sciences, tehran, ir iran mostafa qorbani department of community medicine, alborz university of medical sciences, karaj, ir iran

conclusions although we found an association between myh9 gene polymorphism and urinary albumin excretion, the results did not show a significant association between myh9 polymorphism (rs4821481) and risk of dn in iranian diabetic patients. background myosin heavy chain 9 (myh9) gene polymorphisms have been implicated in different types of renal disease, as well as in nephropathy attributed to ...

2014
Vinícius Sardão Colares Silvia Maria de Oliveira Titan Alexandre da Costa Pereira Patrícia Malafronte Mari M. Cardena Sidney Santos Paulo C. Santos Cíntia Fridman Rui Toledo Barros Viktória Woronik

MYH9 polymorphisms have been described to be associated with the risk of CKD in non-diabetic nephropathy, HIV nephropathy and FSGS. Predominating in black descendants, MHY9 genetic variants could partially explain the excess risk of CKD associated with African ancestry. However, recent data suggests that APOL1 gene co-segregate with MYH9, and could be the gene truly associated with CKD risk. In...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009
Barry I Freedman Pamela J Hicks Meredith A Bostrom Mary E Comeau Jasmin Divers Anthony J Bleyer Jeffrey B Kopp Cheryl A Winkler George W Nelson Carl D Langefeld Donald W Bowden

BACKGROUND Although MYH9 is strongly associated with biopsy-proven idiopathic and HIV-associated focal segmental glomerulosclerosis (FSGS) and clinically diagnosed 'hypertension-associated' end-stage renal disease (ESRD) in African Americans, its role in type 2 diabetes mellitus (T2DM)-associated ESRD is unclear. METHODS To assess whether MYH9 was associated with T2DM-ESRD, 751 African Americ...

2010
Taras K. Oleksyk George W. Nelson Ping An Jeffrey B. Kopp Cheryl A. Winkler

MYH9 was recently identified as renal susceptibility gene (OR 3-8, p < 10(-8)) for major forms of kidney disease disproportionately affecting individuals of African descent. The risk haplotype (E-1) occurs at much higher frequencies in African Americans (> or = 60%) than in European Americans (< 4%), revealing a genetic basis for a major health disparity. The population distributions of MYH9 ri...

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