The effect of oxidants, electrophiles, and NO donors in rat or human erythrocytes was analyzed to investigate the influence of protein sulfhydryl groups on the metabolism of these thiol reactants. Oxidant-evoked alterations in thiolic homeostasis were significantly different in the two models; large amounts of glutathione protein mixed disulfides were produced in rat but not in human erythrocyt...

Forty-five minutes after intraperitoneal injection of a single dose (100 milligrams per kilogram) of L-dihydroxyphenylalanine, the concentration of S-adenosylmethionine in rat brain was lowered by 76 percent. As little as 10 milligrams of L-dihydroxyphenylalanine per kilogram decreased content of S-adenosylmethionine in the adrenal medulla by 51 percent, whereas 100 milligrams per kilogram did ...

I. What Is Syriac? II. Why Study It? a. Biblical Studies b. Patristic Studies c. Liturgical Studies d. Early Syriac Christianity e. Syriac Poetry f. Syriac as a Bridge Culture III. Th e Scope of Syriac Literature IV. Th e Place of Syriac among the Aramaic Dialects V. Tools a. Grammars b. Anthologies of Texts (Chrestomathies) c. Dictionaries d. Main Editions of the Syriac Bible e. Histories of S...

A one-step reductive ligation mediated disulfide formation of S-nitrosothiols was developed. This reaction involves the reaction of the S-nitroso group with phosphine-thioesters to form sulfenamide and thiolate intermediates, which then undergo a fast intermolecular disulfide formation to form stable conjugates. This reaction can be used to design new biosensors of S-nitrosated proteins.