background: laboratory bred sand flies are essential for the study of different biological phenomena including the transmis­sion dynamics of leishmania . the aim of the study was to determine the suitable situation for colonization and main­tenance of iranian strain of phlebotomus papatasi at laboratory conditions from an endemic focus of cutaneous leishmani­asis due to leishmania major . metho...

leishmaniases are a group of sand fly-borne diseases caused by protozoan parasites from species of leishmania genus. these diseases are reported in about 100 countries with a prevalence of 12 million people infected and incidence of 2 million people per year, putting approximately 350 million people at risk of the infections. leishmaniases are endemic and are considered as important public heal...

background: the aim of this study was to assess leishmania infection in sand fly species from areas where leishmaniasis is endemic. this is important for prediction of the risk and expansion of the disease. methods: in this cross-sectional study we used a pcr-based method for detection of leishmania minicircle dna within individual sand flies from orzoieh, a new endemic leishmaniasis focus in s...

background: in turkey, vector control programs are mainly based on indoor residual spraying with pyre­throids against mosquitoes. no special control program is available for sand flies. most insecticide susceptibil­ity tests were done for mosquitoes but not for sand flies. we therefore aimed to determine the insecticide susceptibility against two commonly used insecticides; deltamethrin and per...

leishmaniasis has long been known as a significant public health challenge in many parts of iran. phlebotomus pa­patasi and p. sergent i are the vectors of zoonotic cutaneous leishmaniasis and anthroponotic cutaneous leish­maniasis respectively, and 5 species of sand flies including p. kandelakii , p. neglectus , p. perfiliewi , p. keshishiani and p. alexandri are considered as probable vectors...

Quantitation of the nonlinear heterogeneities in Leishmania parasites, sand fly vectors, and mammalian host relationships provides insights to better understand leishmanial transmission epidemiology towards improving its control. The parasite manipulates the sand fly via production of promastigote secretory gel (PSG), leading to the "blocked sand fly" phenotype, persistent feeding attempts, and...

BACKGROUND Sand fly saliva has been shown to have proteins with potent biological activities, salivary proteins that can be used as biomarkers of vector exposure, and salivary proteins that are candidate vaccines against different forms of leishmaniasis. Sand fly salivary gland transcriptomic approach has contributed significantly to the identification and characterization of many of these sali...

Laboratory colonies of phlebotomine sand flies are necessary for experimental study of their biology, behaviour and mutual relations with disease agents and for testing new methods of vector control. They are indispensable in genetic studies and controlled observations on the physiology and behaviour of sand flies, neglected subjects of high priority. Colonies are of particular value for screen...