Mycobacterium tuberculosis secretes a large number of polypeptides with broad biological and immunological functions. We describe here the characterization of a 28-kDa acid phosphatase of M. tuberculosis (SapM) localized to the culture filtrate. The mature protein demonstrated biochemical characteristics similar to those of the bacterial nonspecific acid phosphatases. However, SapM yielded sign...

Tuberculosis (TB) is responsible for nearly 1.4 million deaths globally every year and continues to remain a serious threat to human health. The problem is further complicated by the growing incidence of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB), emphasizing the need for the development of new drugs against this disease. Phagosomal maturation arrest is an import...

Mycobacterium bovis bacille Calmette-Guerin (BCG) provides only limited protection against pulmonary tuberculosis. We tested the hypothesis that BCG might have retained immunomodulatory properties from its pathogenic parent that limit its protective immunogenicity. Mutation of the molecules involved in immunomodulation might then improve its vaccine potential. We studied the vaccine potential o...

OBJECTIVE The purposes of this study were to compare the efficacy of amoxicillin and cephradine for the treatment of sporadic acute puerperal mastitis (SAPM) and to evaluate the microbiology and clinical parameters of this infection. METHODS We conducted a prospective, randomized, single-blinded study comparing amoxicillin, 500 mg orally q 8 h for 7 days, and cephradine, 500 mg orally q 6 h f...

The recovery of signal parameters from noisy sampled data is an essential problem in digital signal processing. In this paper, we discuss the numerical solution of the following parameter estimation problem. Let h0 be a multivariate exponential sum, i.e., h0 is a finite linear combination of complex exponentials with distinct frequency vectors. Determine all parameters of h0, i.e., all frequenc...

Spatial management tools, such as marine spatial planning and marine protected areas, are playing an increasingly important role in attempts to improve marine management and accommodate conflicting needs. Robust data are needed to inform decisions among different planning options, and early inclusion of stakeholder involvement is widely regarded as vital for success. One of the biggest stakehol...

Riset ini bermaksud buat melukiskan penemuan periset berbentuk Daya guna Penerapan Penjaminan Kualitas lewat Pengakuan dalam Tingkatkan Mutu Jasa Masalah di Majelis hukum Tentara 1- 03 Padang. mengidentifikasi, Awal Aplikasi Program Sertifikasi Kualitas( SAPM) tingkatkan mutu jasa masalah Kedua Aspek pendukung serta penghalang penerapan Ketiga kepada kenaikan memakai pendekatan kualitatif deskr...

The nonlinear bending behavior of sector graphene sheets is studied subjected to uniform transverse loads resting on a Winkler-Pasternak elastic foundation using the nonlocal elasticity theory. Considering the nonlocal differential constitutive relations of Eringen theory based on first order shear deformation theory and using the von-Karman strain field, the equilibrium partial differential eq...

In this paper, it is tried to find an approximate single layer equivalent for multi-layer graphene sheets based on third order non-local elasticity theory. The plates are embedded in two parameter Winkler-Pasternak elastic foundation, and also the thermal effects are considered. A uniform transverse load is imposed on the plates. Applying the non-local theory of Eringen based on third order she...

This study examines the accuracy and value of three different PV module performance modeling approaches by calibrating selected performance models to outdoor IV data measured on different module technologies. We compare measured and modeled IV characteristics by examining the error distributions and correlations with time varying quantities to assess the accuracy of each model for the modules t...