Sciatic is Greek word derived from “Ischiadicus”. The sciatic nerve is also known as the ischiadic nerve or ischiatic nerve, is a large nerve in humans and other animals. It is the longest and widest single nerve in the human body. The sciatic nerve is comprised of five nerves. It is formed on the right and left hand side of the lower spine. It is derived from the spinal nerves L4-S3. It contai...

BACKGROUND Sciatic nerve injury is a disastrous adverse complication of surgery and can cause debilitating pain, functional impairment and poor quality of life. Patients with developmental dysplasia of the hip (DDH) have a high incidence of sciatic nerve injury after total hip arthroplasty (THA). A better understanding of the course of the sciatic nerve in patients with DDH may help minimise th...

INTRODUCTION Sciatic nerve variations are relatively common. These variations are often very significant in several fields of Medicine. The purpose of this paper is to present two such variants and discuss their clinical implications. MATERIAL AND METHODS Three Caucasian cadavers with no prior history of lower limb trauma or surgery were dissected and found to present anatomical variants of t...

Chronic constriction injury to the sciatic nerve was used as an animal model of neuropathic pain. Instead of frequently used reflex-based tests we used an operant thermal place preference test to evaluate signs of neuropathic pain and the effect of baclofen administration in rats with neuropathy. Chronic constriction injury was induced by four loose ligations of the sciatic nerve. Thermal place...

objective: diabetic neuropathy is the most common complication of diabetes mellitus affecting the nervous system. in this study, we investigated the in vivo effects of combined administration of 4-methylcatechol (4-mc) and progesterone (p) as a potential therapeutic tool for sciatic nerve function improvement and its role in histomorphological alterations in diabetic neuropathy in rats. materia...

Objective-Effect of local administration of laminin and fibronectin on nerve regeneration was assessed. Design- Experimental study. Animal- Sixty male Wistar rats. Procedures- The animals were divided into four experimental groups (n=15), randomly: In transected group left sciatic nerve was transected and stumps were fixed in adjacent muscle. In treatment group (CHIT/LF) the defect was bridg...

Abstract Introduction: neuropathy is a condition in which the peripheral nervous system is disrupted. The study of the effects of antioxidants on the performance improvement of this system is vital. This study was aimed at the investigation of the effects of date extract on nerve conduction velocity, distal latency, and wave height of the sciatic nerve in male rats. Materials and Methods: thi...

A 60-year-old man developed severe neuropathic pain and foot-drop in his left leg following resurfacing arthroplasty of the left hip. The pain was refractory to all analgesics for 16 months. At exploration, a PDS suture was found passing through the sciatic nerve at several points over 6 cm and terminating in a large knot. After release of the suture and neurolysis there was dramatic and rapid ...