most common hypotheses of seizure initiation are increased neural excitation, decreased inhibition or both. but, the conditions that lead to these activation states not to be clear yet. recent studies challenge traditional concepts and indicate new evidence that a key epileptogenic process may actually begin in the blood vessel. seizures could be initiate by a variety of insults to the brain, s...

introduction: this study was aimed to asses the rate of recurrence after the first unprovoked seizure in children. methods and materials: in a prospective study, we recruited 145 children who presented with primary unprovoked seizure and were followed for at least 12 months after the first seizure. results: seventy five children (51.7%) experienced subsequent seizures. the cumulative risk of se...

BACKGROUND Mesial temporal lobe epilepsy (mTLE) has been suggested to follow a circadian rhythm. Previous research found an afternoon peak in mTLE seizure occurrence. We evaluated the pattern of seizure occurrence in patients with well-localized mTLE and hypothesized that peak seizure frequency would occur in the afternoon, and that this pattern would not be altered by age, gender, or seizure f...

PURPOSE Long-Term-Monitoring (LTM) is a valuable tool for seizure localization/lateralization among children with refractory-epilepsy undergoing pre-surgical-monitoring. The aim of this study was to examine the factors predicting occurrence of single/multiple seizures in children undergoing pre-surgical monitoring in the LTM unit. METHODS Chart review was done on 95 consecutive admissions on ...

introduction: febrile seizure is the most common type of seizure that occurs in 3– 4% of children below the age of 5 years. the purpose of this study was to determine the frequency of recurrence of febrile and afebrile seizures after the first febrile seizure. methods: in a descriptive prospective study, 139 children (6months to 6years old) admitted between march 2004and august 2005 at yazd sha...

BACKGROUND Few studies have examined seizures in pediatric brain arteriovenous malformation. In our study, risk factors associated with seizure occurrence and long-term seizure control outcomes after different treatments in pediatric arteriovenous malformation patients were investigated. METHODS A retrospective analysis was conducted with clinical data from a cohort of 89 pediatric brain arte...

PURPOSE Febrile seizure, the most common type of pediatric convulsive disorder, is a benign seizure syndrome distinct from epilepsy. However, as epilepsy is also common during childhood, we aimed to identify the prognostic factors that can predict epilepsy in children with febrile seizures. METHODS The study comprised 249 children at the Korea University Ansan Hospital who presented with febr...

OBJECTIVE This study examined the effect of stimulus parameters on the occurrence of adequate seizures and reconsidered the factors related to motor seizure duration. METHODS The medical records of 187 patients who received ECT in Asan Medical Center from January 2007 to May 2014 were retrospectively reviewed. The starting stimulus dose was determined using a preselected-dose method and the c...