serotonin receptors are involved in pathophysiology of schizophrenia and may mediate other neurotransmitter effects. we investigated serotonin receptors gene expression in peripheral blood mononuclear cells (pbmc) of naïve schizophrenic patients, before and after treatment. also serotonin receptor gene expression was compared in two treatment groups including haloperidol and olanzapine. the pbm...

intramascular (im) administration of apomorphine (a mixed d1/d2 dopamine receptors agonist 0.2-1.6 mg/kg) induced pecking, a stereotype behavior in pigeons in a dose- dependent manner. in this study the effect of lithium (li+, 240 mg/kg, im) and ami-193 (a new 5-ht2 antagonist, 0.003 mg/pigeon) on apomorphine-induced peking (aip) were investigated. this study showed that li+ and ami-193 did not...

the effect of endogenous serotonin on long-term potentiation (ltp) in region cai was studied by blocking 5-ht2 receptors with ketanserin in rat hippocampal slices. such a block significantly en-hanced long-term potentiation of the cai population spike induced by high frequency stimulation of the schaffer collateral/ commissural pathway. this implies that serotonin acts on 5-ht2 receptors in cai...

The effect of endogenous serotonin on long-term potentiation (LTP) in region CAI was studied by blocking 5-HT2 receptors with ketanserin in rat hippocampal slices. Such a block significantly en-hanced long-term potentiation of the CAI population spike induced by high frequency stimulation of the schaffer collateral/ commissural pathway. This implies that serotonin acts on 5-HT2 receptors in CAI...

The breast cancer therapies available are insufficient, especially since first-line treatments, such as paclitaxel, result in drug resistance and their toxicity often limits concentration. Strategies like repurposing beneficial, novel treatments can emerge by drugs that interfere with the dopamine serotonin receptors, thus influence tumor growth. In this study, MTT assay was used to test effica...