objective: depression is a major health problem, which is not only underrecognized and undertreated, but is also associated with significant morbidity and mortality. it has been suggested that combination therapy rapidly reduces depressive symptoms in patients with moderate to severe depression and is more effective than monotherapy; but this suggestion remains controversial. serotonergic and n...

a comparison of aggression, anxiety and depression in high school students in saravan city     jenaabadi h [1] , nastiezaie n [2]     received: 23 jan , 2011 accepted: 16 mar, 2011     abstract   . background & aims: the present study aimed to compare aggression, anxiety and depression in high school teenagers in saravan city, november 2010.   materials & methods: this comparative study covered...

objectives: the aim of the current study was to determine the depression status of the elderly and it's related factors. methods & materials: this was a cross sectional study. sample unit was based on the elderly of isfahan city in 2007. 248 elderly aged 60 and older (125 men and 123 women) were selected randomly according to clusters related to the families that are under coverage of isfa...

Endorphins and endorphin agonists play a crucial role in the neural modulation of mood, anxiety, pain and addiction. Recent studies have elucidated the crucial mechanism of enhancing prefrontal cortex influence and dampening limbic and sub cortical influences in depression and remission consistent with the biological profile of endorphin agonists. The historical, biological, experimental and cl...

introduction: depression is one of the most common psychiatric problems. the prevalence of depression in iran has been estimated about 10-35% in females and 5-9% in males. nicotine is a narcotic substance and approximately 22% of american people are dependent on it. one of the notorious outcomes of nicotine-dependency is behavioral problems. the aim of this study was to find the relationship be...

BACKGROUND The significant morbidity and mortality associated with severe depression and its psychotic or melancholic subtypes necessitate effective and well-tolerated therapy. This review evaluates antidepressant treatments for patients with severe depression. DATA SOURCES Comparative clinical trials conducted on patients with severe depression were found by an English-language MEDLINE searc...