In inflammation, the post-transcriptional regulation of transiently expressed genes provides a potential therapeutic target. Tristetraprolin (TTP) is of the factors regulating decay of cytokine mRNAs. The aim of the present study was to identify cytokines whose expression is regulated by TTP. We established a TTP knock-down cell line by expressing shRNA against TTP (shTTP cell line). A cytokine...

We show how to use Kerberos to enable its clients to interact securely with non-Kerberized World Wide Web servers. That is, our protocol does not require that the Web server be a member of a Kerberos realm, and also does not rely on time-synchronization between the participants. In our protocol, the Kerberos client uses the Web server's public-key certi cate to gain cryptographic credentials th...

Existing security mechanisms for serving documents on the World Wide Web typically require use of either an underlying security transport mechanisms (e.g., SSL) or alternate servers, browsers and data streams (e.g., SHTTP). In this paper we introduce a simpler method using plugins which provides moderate security for serving private documents within the standard HTTP mechanism and socket layer....

Widespread growth of open wireless hotspots has made it easy to carry out man-in-the-middle attacks and impersonate web sites. Although HTTPS can be used to prevent such attacks, its universal adoption is hindered by its performance cost and its inability to leverage caching at intermediate servers (such as CDN servers and caching proxies) while maintaining end-to-end security. To complement HT...