Human somatotropin competed for 125I-human somatotropin binding to hepatocytes from female or male rats. Bovine somatotropin and prolactin each inhibited part, but not all, of the uptake of 125I-human somatotropin. The binding of 125I-prolactin was inhibited by human somatotropin and prolactin, but not by bovine somatotropin. Bovine somatotropin and human somatotropin, but not prolactin, compet...

Fetal growth is increased when pregnant gilts are treated with recombinant porcine somatotropin. The mechanism for increased fetal growth was examined by measuring the expression of IGF-I and -II and IGF-binding protein-2 (IGFBP-2) mRNA in liver and reproductive tissues of somatotropin- and saline-treated pregnant gilts. Twenty-four pregnant gilts received daily injections of either saline (con...

The aim of this study was to determine the effect of prepartum somatotropin injection in late-pregnant Holstein heifers on metabolism, milk production and resumption of postpartum ovulation. For this study, 31 late-pregnant Holstein heifers were used. The heifers were assigned randomly into two treatments: (1) 500 mg sc injections of somatotropin (somatotropin treatment, n = 15) at -35 and -21 ...

A primary goal of exogenous somatotropin treatment is to increase lean body mass. This is accomplished, in part, by increasing the efficiency with which dietary amino acids are used for protein deposition. Somatotropin administration also improves protein balance by minimizing the loss of protein during fasting and maximizing the protein gained during meal absorption. Amino acid catabolism is d...

Bovine somatotropin (bST) has been isolated from pituitary glands and compared in a variety of chemical analyses and bioassays with somatotropin derived from recombinant Escherichia coli. Comparison of pituitary extracts and purified bST by Western blot analysis of two-dimensional gels suggested that the immunoreactive somatotropin species present in the extract were also present in the purifie...

Use of bovine somatotropin to increase product ion of milk and milk solids poses the problem of allocation within herd and implications for genetic evaluatat ion records with and without bovine somatotropin were simulated for different correlations between performance with and without t reatment and response to it. Resulting within-herd variances and accuracy and bias in sire evaluations were c...

Pituitary somatotropin (growth hormone) and prolactin are two related protein hormones produced by the pituitary gland. Both contain single polypeptide chains of 190-200 amino acid residues (Wallis, 1978). In mammals, prolactin acts primarily on the mammary glands, promoting mammary growth and lactation; in many species it also has direct effects on the gonads and possibly other organs (Horrobi...

Mammalian prolactin stimulates growth and inhibits metamorphosis of larvae of several species of amphibians. Mammalian somatotropin has little or no effect upon larval growth or metamorphosis unless used in high concentrations. The evidence behind these statements and some of the implications are critically evaluated. Growth of postmetamorphic amphibians is stimulated by somatotropin but not by...

Catfish is one of the most important freshwater fish farming commodities in Indonesia. Higher catfish production can be achieved by cultivating transgenic carrying growth hormone (GH) gene African (Clarias gariepinus GH, CgGH). This research focuses on analysis presence CgGH G1, G2, and G3 mutiara broodstock, as an indication stable inheritance. was isolated using RNeasy mini kit RT-PCR. RT-PCR...

Bovine somatotropin (bST) increases milk production in dairy animals. The maximum increase in milk production has been observed up to 41%. Somatotropin did not change milk composition significantly. During short-term application of bST, cows mobilized their body-reserves to support the increased milk production. Although DM intake of cows was increased in the long-term applications, however, gr...